Journal ArticleDOI
2012 Update of the Canadian Cardiovascular Society Guidelines for the Diagnosis and Treatment of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult
Todd J. Anderson,Jean Grégoire,Robert A. Hegele,Patrick Couture,G.B. John Mancini,Ruth McPherson,Gordon A. Francis,Paul Poirier,David C.W. Lau,Steven A. Grover,Jacques Genest,André C. Carpentier,Robert Dufour,Milan Gupta,Richard Ward,Lawrence A. Leiter,Eva Lonn,Dominic S. Ng,Glen J. Pearson,Gillian M. Yates,James A. Stone,Ehud Ur +21 more
TLDR
An updated version of the CCS Dyslipidemia guidelines is presented, incorporating new recommendations based on recent findings and harmonizing CCS guidelines with those from other Societies, to increase the appropriate use of evidence-based cardiovascular disease event risk assessment in the management of dys Lipidemia.About:
This article is published in Canadian Journal of Cardiology.The article was published on 2013-02-01. It has received 754 citations till now. The article focuses on the topics: Framingham Risk Score & Canadian Cardiovascular Society.read more
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Journal ArticleDOI
Guidelines for the Early Management of Patients With Acute Ischemic Stroke A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association
William J. Powers,Alejandro A. Rabinstein,Teri Ackerson,Opeolu Adeoye,Nicholas C. Bambakidis,Kyra J. Becker,José Biller,Michael D. Brown,Bart M. Demaerschalk,Brian L. Hoh,Edward C. Jauch,Chelsea S. Kidwell,Thabele M Leslie-Mazwi,Bruce Ovbiagele,Phillip A. Scott,Kevin N. Sheth,Andrew M. Southerland,Deborah V. Summers,David L. Tirschwell +18 more
TL;DR: These guidelines supersede the prior 2007 guidelines and 2009 updates and support the overarching concept of stroke systems of care and detail aspects of stroke care from patient recognition; emergency medical services activation, transport, and triage; through the initial hours in the emergency department and stroke unit.
Journal ArticleDOI
2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
David C. Goff,Donald M. Lloyd-Jones,Glen C. Bennett,Sean Coady,Ralph B. D'Agostino,Raymond J. Gibbons,Philip Greenland,Daniel T. Lackland,Daniel Levy,Christopher J. O'Donnell,Jennifer G. Robinson,J. Sanford Schwartz,Susan T. Shero,Sidney C. Smith,Paul D. Sorlie,Neil J. Stone,Peter W.F. Wilson +16 more
TL;DR: Harmon S. Jordan, ScD, Lev Nevo, MD, Janusz Wnek, PhD Jeffrey L. Anderson,MD, FACC, FAHA, Chair-Elect, Nancy M. Halperin, PhD.
Journal ArticleDOI
2013 ACC/AHA Guideline on the Assessment of Cardiovascular Risk
David C. Goff,Donald M. Lloyd-Jones,Faha Glen Bennett,Sean Coady,Jennifer G. Robinson,J. Sanford Schwartz,Raymond J. Gibbons,Susan T. Shero,Philip Greenland,Sidney C. Smith,Daniel T. Lackland,Paul D. Sorlie,Daniel Levy,Neil J. Stone +13 more
TL;DR: The ACC and AHA have collaborated with the National Heart, Lung, and Blood Institute and stakeholder and professional organizations to develop guidelines, standards, and policies that promote optimal patient care and cardiovascular health.
Journal ArticleDOI
Efficacy and Safety of Alirocumab in Reducing Lipids and Cardiovascular Events
Jennifer G. Robinson,Michel Farnier,Michel Krempf,Jean Bergeron,Gérald Luc,Maurizio Averna,Erik S.G. Stroes,Gisle Langslet,Frederick J. Raal,Mahfouz El Shahawy,Michael J. Koren,Norman E. Lepor,Christelle Lorenzato,Robert Pordy,Umesh Chaudhari,John J.P. Kastelein +15 more
TL;DR: Over a period of 78 weeks, alirocumab, when added to statin therapy at the maximum tolerated dose, significantly reduced LDL cholesterol levels and there was evidence of a reduction in the rate of cardiovascular events.
Journal ArticleDOI
Overview of epidemiology and contribution of obesity to cardiovascular disease.
TL;DR: The evidence reviewed in this paper suggests that adipose tissue quality/function is as important, if not more so, than its amount in determining the overall health and CV risks of overweight/obesity.
References
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Journal ArticleDOI
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.
William C. Knowler,Elizabeth Barrett-Connor,Sarah E. Fowler,Richard F. Hamman,John M. Lachin,Elizabeth A. Walker,David M. Nathan +6 more
TL;DR: In this paper, the authors compared a lifestyle intervention with metformin to prevent or delay the development of Type 2 diabetes in nondiabetic individuals. And they found that the lifestyle intervention was significantly more effective than the medication.
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GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
Gordon H. Guyatt,Andrew D Oxman,Gunn Elisabeth Vist,Regina Kunz,Yngve Falck-Ytter,Pablo Alonso-Coello,Holger J. Schünemann +6 more
TL;DR: The advantages of the GRADE system are explored, which is increasingly being adopted by organisations worldwide and which is often praised for its high level of consistency.
Journal ArticleDOI
Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study
Salim Yusuf,Steven Hawken,Stephanie Ôunpuu,Tony Dans,Alvaro Avezum,Fernando Lanas,Matthew J. McQueen,Andrzej Budaj,Prem Pais,John Varigos,Liu Lisheng +10 more
TL;DR: Abnormal lipids, smoking, hypertension, diabetes, abdominal obesity, psychosocial factors, consumption of fruits, vegetables, and alcohol, and regular physical activity account for most of the risk of myocardial infarction worldwide in both sexes and at all ages in all regions.
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The metabolic syndrome—a new worldwide definition
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European Guidelines on Cardiovascular Disease Prevention in Clinical Practice (Version 2012)
Massimo Piepoli,Arno W. Hoes,Stefan Agewall,Christian Albus,Carlos Brotons,Alberico L. Catapano,Marie Therese Cooney,Ugo Corrà,Bernard Cosyns,Christi Deaton,Ian D. Graham,Michael Stephen Hall,FD Richard Hobbs,Maja Lisa Løchen,Herbert Löllgen,Pedro Marques-Vidal,Joep Perk,Eva Prescott,Josep Redon,Dimitrios J. Richter,Naveed Sattar,Y.M. Smulders,Monica Tiberi,H. Bart van der Worp,Ineke van Dis,W M Monique Verschuren +25 more
TL;DR: In this paper, a randomized clinical trial was conducted to evaluate the effect of preterax and Diamicron Modified Release Controlled Evaluation (MDE) on the risk of stroke.
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