Open Access
5-Aminolevulinic Acid (5-ALA) : a precursor of heme : Fermentation, metabolism and usage
Urara Ota,Hidemitsu Sugihara,Fuminori Abe +2 more
- Vol. 2, Iss: 1, pp 3-17
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The article was published on 2013-01-01 and is currently open access. It has received 7 citations till now. The article focuses on the topics: Heme.read more
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Journal ArticleDOI
5-amino levulinic acid inhibits SARS-CoV-2 infection in vitro.
Yasuteru Sakurai,Mya Myat Ngwe Tun,Yohei Kurosaki,Takaya Sakura,Daniel Ken Inaoka,Kiyotaka Fujine,Kiyoshi Kita,Kouichi Morita,Jiro Yasuda +8 more
TL;DR: In this paper, 5-amino levulinic acid (5-ALA) was used as an antiviral drug candidate for COVID-19 pandemic in cell culture.
Posted ContentDOI
5-amino levulinic acid inhibits SARS-CoV-2 infection in vitro
Yasuteru Sakurai,Mya Myat Ngwe Tun,Yohei Kurosaki,Takaya Sakura,Daniel Ken Inaoka,Kiyotaka Fujine,Kiyoshi Kita,Kouichi Morita,Jiro Yasuda +8 more
TL;DR: 5-ALA treatment potently inhibited infection of SARS-CoV-2, a causative agent of COVID-19, and the antiviral effects could be detected in both human and non-human cells, without significant cytotoxicity.
Journal ArticleDOI
Impact of 5-aminolevulinic acid with iron supplementation on exercise efficiency and home-based walking training achievement in older women.
Shizue Masuki,Atsumi Morita,Yoshi-ichiro Kamijo,Shigeki Ikegawa,Yufuko Kataoka,Yu Ogawa,Eri Sumiyoshi,Kiwamu Takahashi,Tohru Tanaka,Motowo Nakajima,Hiroshi Nose +10 more
TL;DR: It is found that ALA+SFC supplementation augmented exercise efficiency and thereby improved IWT achievement in older women.
Journal ArticleDOI
In Vivo Curative and Protective Potential of Orally Administered 5-Aminolevulinic Acid plus Ferrous Ion against Malaria
Shigeo Suzuki,Kenji Hikosaka,Emmanuel Oluwadare Balogun,Emmanuel Oluwadare Balogun,Emmanuel Oluwadare Balogun,Keisuke Komatsuya,Mamoru Niikura,Fumie Kobayashi,Kiwamu Takahashi,Tohru Tanaka,Motowo Nakajima,Kiyoshi Kita,Kiyoshi Kita +12 more
TL;DR: In this paper, a combination of Aminolevulinic acid (ALA) and ferrous ion (Fe(2+)) inhibits the in vitro growth of the human malaria parasite Plasmodium falciparum.
Journal ArticleDOI
Photodynamic detection of canine mammary gland tumours after oral administration of 5‐aminolevulinic acid
Tomohiro Osaki,Inoru Yokoe,Shun-ichiro Ogura,K. Takahashi,K. Murakami,K Inoue,Masahiro Ishizuka,T. Tanaka,Liming Li,Akihiko Sugiyama,Kazuo Azuma,Yusuke Murahata,Takeshi Tsuka,Norihiko Ito,Tomohiro Imagawa,Yoshiharu Okamoto +15 more
TL;DR: The pharmacokinetics of 5-ALA-induced porphyrins and its effectiveness in PDD in dogs with mammary gland tumours (MGTs) following oral administration are evaluated, suggesting that 5- ALA-PDD might be an effective diagnostic tool for MGTs.