A Case of Contagious Ecthyma (Orf Virus) in a Nonmanipulated Laboratory Dorset Sheep (Ovis aries)
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An approximately 5-month-old laboratory wether presented with a continuum of lesions from hemorrhagic papules, vesicles, and pustules, to multifocal necrotic scabs at the commissure of the lips, medial canthus of the left eye, and distal prepuce, confirming the diagnosis of Orf virus (ORFV).Abstract:
An approximately 5-month-old laboratory wether, originating from a local vendor with a closed flock and maintained on a preventative medicine plan, presented with a continuum of lesions from hemorrhagic papules, vesicles, and pustules, to multifocal necrotic scabs at the commissure of the lips, medial canthus of the left eye, and distal prepuce. A presumptive diagnosis of Orf virus (ORFV) was made and the sheep was euthanized. A full necropsy was performed, and histopathological evaluation of affected tissues revealed multifocal-to-coalescing necrotizing and proliferative cheilitis and dermatitis with eosinophilic intracytoplasmic inclusion bodies. Electron microscopy findings revealed degenerate keratinocytes containing numerous typical 200–300 nm wide cytoplasmic parapoxvirus virions, confirming the diagnosis of ORFV. We believe that this animal developed a clinical case of ORFV either due to an adverse reaction to an ORFV vaccine, or this animal had a case of preexisting ORFV which manifested after arrival at our facility.read more
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An association of Orf virus infection among sheep and goats with herd health programme in Terengganu state, eastern region of the peninsular Malaysia.
Jamilu Abubakar Bala,Jamilu Abubakar Bala,Krishnan Nair Balakrishnan,Ashwaq Ahmed Abdullah,Ashwaq Ahmed Abdullah,Lawan Adamu,Muhammad Syaafii bin Noorzahari,Lau Kah May,Hassana Kyari Mangga,Hassana Kyari Mangga,Mohd Termizi Ghazali,Ramlan Bin Mohamed,Abd Wahid Haron,Mustapha Mohamed Noordin,Mohd Azmi Mohd Lila +14 more
TL;DR: There was a high sporadic prevalence of Orf infection in this region, which indicated a good herd health programme should be in place, in order to prevent and control disease transmission as well as to improve herd immunity.
Journal ArticleDOI
Dermatopathology of Orf Virus (Malaysian Isolates) in Mice Experimentally Inoculated at Different Sites with and without Dexamethasone Administration.
Jamilu Abubakar Bala,Jamilu Abubakar Bala,Krishnan Nair Balakrishnan,Ashwaq Ahmed Abdullah,Ashwaq Ahmed Abdullah,Tay Kimmy,Yusuf Abba,Yusuf Abba,Ramlan Bin Mohamed,Faez Firdaus Abdullah Jesse,Abd Wahid Haron,Mustapha Mohamed Noordin,Asinamai Athliamai Bitrus,Idris Umar Hambali,Mohd Azmi Mohd Lila +14 more
TL;DR: Intradermal inoculation with UPM1/14 or UPM2/14 isolate produced a mild skin lesion in mice, and there was no significant difference in orf disease manifestation despite variation of inoculation sites.
Journal ArticleDOI
Occurrence and identification of contagious ecthyma in blackbuck.
Anil Kumar Sharma,Gnanavel Venkatesan,Karikalan Mathesh,Hira Ram,Muthanan Andavar Ramakrishnan,Awadh Bihari Pandey +5 more
TL;DR: Comparison of B2L gene sequence analysis andylogenetic analysis revealed the same evolutionary relationship that the virus isolate from blackbuck is closely related to Indian isolates and this seems to be the first report of orf in blackbuck from Indian subcontinent.
Journal ArticleDOI
Contagious ecthyma: how serious is the disease worldwide?
Zaharaddeen Lawan,Jamilu Abubakar Bala,Alhaji Modu Bukar,Krishnan Nair Balakrishnan,Hassana Kyari Mangga,Faez Firdaus Jesse Abdullah,Mustapha Mohamed Noordin,M. L. Mohd-Azmi +7 more
TL;DR: Contagious ecthyma (CE) is an infectious disease of small ruminants caused by a parapoxvirus of family Poxviridae subfamily Chordopoxvirinae as discussed by the authors.
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