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Book ChapterDOI

A Numerical Representation Method for a DNA Sequence Using Gray Code Method

TLDR
In this paper, a simple numerical mapping method is proposed in which the optimum descriptor value is obtained by applying Gray code concept, the proposed method is evaluated on benchmark databases HRM195 and ASP67 for an identification of protein coding region application.
Abstract
The exceptional speed in increase of genomic data at public databases requires advanced computational tools to perform quick gene analysis. The tools can be devised with the aid of genomic signal processing. The pivotal task in genomic signal processing is numerical mapping. In numerical mapping, the string of nucleotides is transformed into discrete numerical sequence by assigning optimum mathematical descriptor to a nucleotide. The descriptor must be compatible with the further stages of genomic application in order to achieve high efficiency. In this work, a simple numerical mapping method is proposed in which the optimum descriptor value is obtained by applying Gray code concept. The proposed method is evaluated on benchmark databases HRM195 and ASP67 for an identification of protein coding region application. The proposed method exhibits improved exon prediction efficiency in terms of performance accuracy and equal error rate when compared with similar methods.

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Citations
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Journal ArticleDOI

Detection of exon location in eukaryotic DNA using a fuzzy adaptive Gabor wavelet transform

TL;DR: The proposed approach has an immense plus point of being capable of isolating detailed sub-regions in each exon efficiently proving its efficacy comparing with existing techniques.
Journal ArticleDOI

DNA numerical encoding schemes for exon prediction: a recent history.

TL;DR: In this paper, a review of existing encoding (mapping) schemes was devised for the exon detection accuracy, and a comparative analysis was formulated to emphasize the importance of the genetic code setting of amino acids considered for application related to computational elucidation for exon Detection.
Book ChapterDOI

Signal processing applications in molecular sequencing—A systematic review

TL;DR: This chapter discusses various DSP algorithms involved in the study of genome series along with their respective advantages and disadvantages.
Journal ArticleDOI

The Effect of Numerical Mapping Techniques on Performance in Genomic Research

TL;DR: In this article , a review of all digital coding techniques presented in the literature in the studies conducted in the last 10 years have been examined, and the numerical representations of these techniques are given in a sample DNA sequence.
References
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Journal ArticleDOI

Biological identifications through DNA barcodes

TL;DR: It is established that the mitochondrial gene cytochrome c oxidase I (COI) can serve as the core of a global bioidentification system for animals and will provide a reliable, cost–effective and accessible solution to the current problem of species identification.
Journal ArticleDOI

Evolution of long-range fractal correlations and 1/f noise in DNA base sequences.

TL;DR: Spectral density measurements of individual base positions demonstrate the ubiquity of low-frequency 1/f β noise and long-range fractal correlations as well as prominent short-range periodicities.
Journal ArticleDOI

Genomic signal processing

TL;DR: Digital signal processing provides a set of novel and useful tools for solving highly relevant problems in genomic information science and technology, in the form of local texture, color spectrograms visually provide significant information about biomolecular sequences which facilitates understanding of local nature, structure, and function.
Journal ArticleDOI

ACE-inhibition induces a cardioprotective transcriptional response in the metabolic syndrome heart

TL;DR: It is concluded that MetS and control murine hearts have unique transcriptional profiles and exhibit a partially specific transcriptional response to ACE-inhibition, which appears to counteract some of the MetS-specific pathways, while also activating cardioprotective mechanisms.
Related Papers (5)
Trending Questions (1)
How can DNA be expressed mathematically?

The paper proposes a numerical mapping method using the Gray code concept to express DNA sequences mathematically.