Journal ArticleDOI
A primate model of anxiety
Gautam Palit,Rakesh Kumar,S.R. Chowdhury,Mukut B Gupta,Ram C Saxena,Rikhab C. Srimal,Dhawan Bn +6 more
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TLDR
The model, thus, seems suitable for evaluation of potential anxiolytic agents and indicates the specificity of its anxiogenic response.About:
This article is published in European Neuropsychopharmacology.The article was published on 1998-08-01. It has received 23 citations till now. The article focuses on the topics: Anxiogenic & Buspirone.read more
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The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders: Update 2009 on the Treatment of Acute Mania
Heinz Grunze,Eduard Vieta,Guy M. Goodwin,Charles L. Bowden,Rasmus Wentzer Licht,Hans-Jürgen Möller,Siegfried Kasper +6 more
TL;DR: These updated guidelines are based on a first edition that was published in 2003, and have been edited and updated with the available scientific evidence until end of 2008.
Journal ArticleDOI
Modeling seizure-related behavioral and endocrine phenotypes in adult zebrafish
Keith Wong,Adam Stewart,Thomas Gilder,Nadine Wu,Kevin Frank,Siddharth Gaikwad,Christopher Suciu,John DiLeo,Eli Utterback,Katie Chang,Leah Grossman,Jonathan Cachat,Allan V. Kalueff +12 more
TL;DR: Paralleling behavioral and endocrine phenotypes observed in clinical and rodent studies, the data implicates adult zebrafish as an emerging experimental model for epilepsy research.
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Non-Human Primates: Model Animals for Developmental Psychopathology
Eric E. Nelson,James T. Winslow +1 more
TL;DR: It is argued that primates are uniquely capable of uncovering interactions between genes, environmental challenges, and development resulting in altered risk for psychopathology.
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Isatin: role in stress and anxiety.
TL;DR: The possibility that isatin and its analogues may be interesting new pharmacological agents is suggested; Isatin antagonists may be anxiolytic, and isatin agonists may activate the HPA axis.
Journal ArticleDOI
Non-human primate models for investigating fear and anxiety.
Marilia Barros,Carlos Tomaz +1 more
TL;DR: This review focuses on the available non-human primate models for investigating fear/anxiety, addressing their advantages, shortcomings, and conceptual framework on which they are based and a new ethologically based model to study anxiety and fear-induced avoidance in callitrichids--the marmoset predator confrontation test--is discussed.
References
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Book
Harrison's Principles of Internal Medicine
TL;DR: In this article, Cardinal Manifestations of Disease Genetics and Disease Clinical Pharmacology Nutrition Infectious Disease Disorders Of The Cardiovascular System Disorders Of the Kidney And Urinary Tract Disorders Of Gastrointestinal System Disorders of The Immune System, Connective Tissue And Joints Hematology And Oncology Endocrinology And Metabolism Neurologic Disorders Environmental And Occupational Hazards.
Book
Psychopharmacology: The Fourth Generation of Progress
Floyd E. Bloom,David J. Kupfer +1 more
TL;DR: Part 1 Preclinical section: critical analysis of methods transmitter systems - amino acids, amines, peptides, new transmitterscritical analysis of integrative concepts.
Journal ArticleDOI
Interaction of convulsive ligands with benzodiazepine receptors.
TL;DR: During structural modification of ethyl beta-carboline-3-carboxylate an agent was discovered which has high affinity for brain benzodiazepine receptors but which is a potent convulsant, which may explain the convulsive properties.
Journal ArticleDOI
5-HT1A receptor agonists: recent developments and controversial issues
TL;DR: Most evidence points towards a critical involvement of presynaptic receptors in the anxiolytic effects of 5-HT1A receptor agonists (although a possible contribution of postsynaptic receptors cannot be excluded) and a case can be made for the reverse; i.e., a strong involvement of post Synaptic receptors and a questionable contribution of presyaptic receptors.
Journal ArticleDOI
Yohimbine induced anxiety and increased noradrenergic function in humans: effects of diazepam and clonidine.
TL;DR: Findings indicate that noradrenergic hyperactivity may be a factor in the production of some anxiety states and the anti-anxiety effects of clonidine appear to result from its actions on receptors which decrease nor adrenergic activity.
Related Papers (5)
A two-compartment exploratory model to study anxiolytic/anxiogenic effects of drugs in the rat.
E. Merlo Pich,Rosario Samanin +1 more