Journal ArticleDOI
A review of adaptive mechanisms in cell responses towards oxidative stress caused by dental resin monomers
TLDR
The aim of the present review manuscript is to discuss adaptive cell responses to oxidative stress caused by monomers, and the particular significance of a tightly controlled network of non-enzymatic as well as enzymatic antioxidants for the regulation of cellular redox homeostasis and antioxidant defense in monomer-exposed cells will be addressed.About:
This article is published in Biomaterials.The article was published on 2013-06-01. It has received 235 citations till now. The article focuses on the topics: Oxidative stress.read more
Citations
More filters
How much do resin-based dental materials release? A meta-analytical approach (vol 27 pg 723, 2011)
Kirsten Van Landuyt,Tim S. Nawrot,Ben Geebelen,Jan De Munck,Johan Snauwaert,Kumiko Yoshihara,Hans Scheers,Lode Godderis,Peter Hoet,Bart Van Meerbeek +9 more
TL;DR: This meta-analytical study reviewed the literature on the short- and long-term release of components from resin-based dental materials, and to determine how much of those components may leach out in the oral cavity.
Journal ArticleDOI
From Artisanal to CAD-CAM Blocks: State of the Art of Indirect Composites.
TL;DR: This critical state-of-the-art review analyzes the strengths and weaknesses of the different varieties of CAD-CAM composite materials, especially as compared with direct and artisanal indirect composites and suggests manufacturers should provide more complete information regarding their product polymerization process, microstructure, and composition.
Journal ArticleDOI
Cariogenic Bacteria Degrade Dental Resin Composites and Adhesives
TL;DR: It is hypothesized that S. mutans has esterase activities at levels that degrade resin composites and adhesives; degree of degradation was dependent on the material’s chemical formulation.
Journal ArticleDOI
Biocompatibility of polymer-based biomaterials and medical devices - regulations, in vitro screening and risk-management.
TL;DR: A risk-management approach towards the judicial choice of in vitro tests throughout the development and production of medical devices and drug delivery systems will facilitate rapid regulatory approval, avoid unnecessary animal studies, and ultimately reduce risks for patients.
Journal ArticleDOI
Polydopamine-Templated Hydroxyapatite Reinforced Polycaprolactone Composite Nanofibers with Enhanced Cytocompatibility and Osteogenesis for Bone Tissue Engineering
Xiang Gao,Jinlin Song,Ping Ji,Xiaohong Zhang,Xiaoman Li,Xiao Xu,Mengke Wang,Siqi Zhang,Yi Deng,Feng Deng,Shicheng Wei +10 more
TL;DR: This study demonstrated that the developed tHA/PCL composite nanofibers with enhanced cytocompatibility and osteogenic capacity hold great potential as scaffolds for bone tissue engineering.
References
More filters
Journal ArticleDOI
Free Radicals in the Physiological Control of Cell Function
TL;DR: There is growing evidence that aging involves, in addition, progressive changes in free radical-mediated regulatory processes that result in altered gene expression.
Journal ArticleDOI
Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple.
TL;DR: Estimates can be used to more fully understand the redox biochemistry that results from oxidative stress, which hopefully will provide a rationale and understanding of the cellular mechanisms associated with cell growth and development, signaling, and reductive or oxidative stress.
Journal ArticleDOI
Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions.
Gray W. Pearson,Fred L. Robinson,Tara Beers Gibson,Bing E. Xu,Mahesh Karandikar,Kevin S. Berman,Melanie H. Cobb +6 more
TL;DR: Nonenzymatic mechanisms that impact MAP kinase functions and findings from gene disruption studies are highlighted and particular emphasis is on ERK1/2.
Journal ArticleDOI
Superoxide Radical and Superoxide Dismutases
TL;DR: O2- oxidizes the [4Fe-4S] clusters of dehydratases, such as aconitase, causing-inactivation and release of Fe(II), which may then reduce H2O2 to OH- +OH..
Journal ArticleDOI
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
Benoit Dérijard,Benoit Dérijard,Masahiko Hibi,I-Huan Wu,I-Huan Wu,Tamera Barrett,Bing Su,Tiliang Deng,Michael Karin,Roger J. Davis,Roger J. Davis +10 more
TL;DR: JNK1 is a component of a novel signal transduction pathway that is activated by oncoproteins and UV irradiation and its properties indicate that JNK1 activation may play an important role in tumor promotion.