Journal ArticleDOI
A review of anti-infective and anti-inflammatory chalcones.
TLDR
This review is complementary to earlier reviews and covers more recent reports of antimicrobial activity of chalcones (antibacterial and antifungal), as well as antileishmanial, antimalarial, antiviral and anti-inflammatory activities of these compounds.About:
This article is published in European Journal of Medicinal Chemistry.The article was published on 2007-02-01. It has received 956 citations till now. The article focuses on the topics: Antibacterial agent.read more
Citations
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Recent developments in biological activities of chalcones: a mini review.
TL;DR: This review article focuses on the recent developments (2010-2014) on various pharmacological and medicinal aspects of chalcones and their analogues.
Journal ArticleDOI
Cytotoxicity, antiviral and antimicrobial activities of alkaloids, flavonoids, and phenolic acids
TL;DR: In vitro antiviral, antibacterial, and antifungal activities and cytotoxicity of natural products tested may constitute a preliminary step for further relevant studies to identify the mechanism of action.
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Plants as sources of new antimicrobials and resistance-modifying agents
TL;DR: The aim of this article is to review the advances in in vitro and in vivo studies on the potential chemotherapeutic value of phytochemical products and plant extracts as RMAs to restore the efficacy of antibiotics against resistant pathogenic bacteria.
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Fruit polyphenols, immunity and inflammation
TL;DR: Evidence for the effects of fruit and tea flavonoids and their metabolites in inflammation and immunity is summarized and Mechanisms of effect are discussed, including those on enzyme function and regulation of gene and protein expression.
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Dietary phytochemicals and their potential effects on obesity: a review.
TL;DR: The progresses made in understanding of obesity are summarized, including the role of inflammation process, the recently understood endocrine function of adipose tissue, as well as passive roles of processes of energy storage and adipogenesis related to fat cell lifecycle: differentiation, maturation, and apoptosis.
References
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Journal ArticleDOI
Flavonoids : old and new aspects of a class of natural therapeutic drugs
TL;DR: This review summarizes available data on these beneficial effects of flavonoids and suggests that the compounds may possess significant antihepatotoxic, antiallergic, anti-inflammatory, antiosteoporotic and even antitumor activities.
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Chalcones: an update on cytotoxic and chemoprotective properties.
Mei-Lin Go,X. Wu,X. L. Liu +2 more
TL;DR: The thiol reactivity of chalcones is likely to contribute to both cytotoxic and chemoprotective properties of these compounds.
Journal Article
Bioactivities of chalcones.
TL;DR: In this article, the authors outline the different bioactivities of a variety of chalcones and describe the cytotoxic, anticancer, chemopreventative and mutagenic properties of a number of CHs followed by an account of various CHs as antimicrobial agents.
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Chalcones and flavonoids as anti-tuberculosis agents.
TL;DR: A hydrophobic substituent on one aromatic ring, and a hydrogen-bonding group on the other aromatic ring resulted in increased anti-TB activity of the chalcones and chalcone-like compounds.