Journal ArticleDOI
A rule to predict which enantiomer of a secondary alcohol reacts faster in reactions catalyzed by cholesterol esterase, lipase from Pseudomonas cepacia, and lipase from Candida rugosa
Romas J. Kazlauskas,Romas J. Kazlauskas,Alexandra N. E. Weissfloch,Aviva Rappaport,Louis A. Cuccia +4 more
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This article is published in Journal of Organic Chemistry.The article was published on 1991-04-01. It has received 870 citations till now. The article focuses on the topics: Lipase & Candida rugosa.read more
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Chemoenzymatic Stereoselective Synthesis of trans-Flavan-4-ols via Lipase-Catalyzed Kinetic Resolutions
TL;DR: In this article, a series of trans-flavan-4-ols bearing different substitution patterns in the aromatic ring were used as biocatalysts for stereoselective acylation reactions.
Studies on the incorporation of lipase in synthetic polymerisable vesicles
TL;DR: This thesis describes studies on the suitability of synthetic polymerisable vesicles for the incorporation and stabilisation of lipase for the bioconversion of organic chemical compounds and found that polymerised vesicle systems are considerably more stable than their nonpolymerised analogues.
Journal ArticleDOI
Enzymatic synthesis of enantiomerically pure 1,2-fluorocyclopentanols and 1,2-aminofluorocyclopentanes
TL;DR: This work has confirmed that 2-Fluorocyclopentanols can be converted to prostaglandin F2a precursors, while 2-substituted cyclopentanol are the starting compounds for the preparation of L7 leukotriene B4, a conformationally restricted leukOTriene antagonist used in the enantioselective general synthesis of (+)-Estron and Desogestrel.
Dissertation
Chemo-enzymatische asymmetrische Synthesen mit DHAP-Aldolasen
TL;DR: The DHAP-Aldolasen stellen durch relativ breite Substrattoleranz und ihre hohe Stereospezifitat ein sehr interessantes Werkzeug dar, um neue komplexe Naturstoff-Analoga herzustellen.