Journal ArticleDOI
A rule to predict which enantiomer of a secondary alcohol reacts faster in reactions catalyzed by cholesterol esterase, lipase from Pseudomonas cepacia, and lipase from Candida rugosa
Romas J. Kazlauskas,Romas J. Kazlauskas,Alexandra N. E. Weissfloch,Aviva Rappaport,Louis A. Cuccia +4 more
Reads0
Chats0
About:
This article is published in Journal of Organic Chemistry.The article was published on 1991-04-01. It has received 870 citations till now. The article focuses on the topics: Lipase & Candida rugosa.read more
Citations
More filters
Journal ArticleDOI
Application of Lecitase® Ultra-Catalyzed Hydrolysis to the Kinetic Resolution of (E)-4-phenylbut-3-en-2-yl Esters
TL;DR: In this paper, the possibility of using Lecitase® Ultra as a novel alternative biocatalyst for the kinetic resolution of model racemic allyl esters of (E)-4-phenylbut-3-en-3ol: Acetate (4a) and propionate(4b) through their enantioselective hydrolysis was investigated.
Journal ArticleDOI
Synthesis of Both Enantiomers of Conduritol C Tetraacetate and of meso-Conduritol D Tetraacetate by Oxidation of Benzoquinone Bis(ethylene acetal)
Martin Lang,Thomas Ziegler +1 more
TL;DR: In this article, the enantiomerically pure triacetates were converted into both enantiomers of conduritol C tetraacetate 13 as described for the racemic compounds.
Journal ArticleDOI
Transition-state model for subtilisin-catalyzed transesterifications of secondary alcohols
Tadashi Ema,Ryoichi Okada,Minoru Fukumoto,Masahito Jittani,Mikiko Ishida,Kenji Furuie,Kunihiro Yamaguchi,Takashi Sakai,Masanori Utaka +8 more
TL;DR: In this paper, a transition-state model capable of explaining the S -preference of subtilisin toward secondary alcohols has been proposed to explain the chiral discrimination in the transition state.
Journal ArticleDOI
Lipase-catalyzed resolution and desymmetrization of 2-hydroxymethylaziridines
TL;DR: In this paper, the Amano PS lipase-catalyzed acetylation of 2-hydroxymethylaziridines 1a-e has been investigated in order to evaluate the effect of ring substituents on the enantioselectivity of the reaction and to assess the stereochemical preference of the enzyme.
Journal ArticleDOI
Asymmetric hydrolyses of 1,2‐ and 1,3‐diacetoxycyclohexanes with the cultured suspension cells of Marchantia polymorpha
TL;DR: Findings indicate that cultured cells of Marchantia polymorpha hydrolyze the acetoxyl groups enantioselectively at the stereogenic center of R-configuration.