Journal ArticleDOI
A rule to predict which enantiomer of a secondary alcohol reacts faster in reactions catalyzed by cholesterol esterase, lipase from Pseudomonas cepacia, and lipase from Candida rugosa
Romas J. Kazlauskas,Romas J. Kazlauskas,Alexandra N. E. Weissfloch,Aviva Rappaport,Louis A. Cuccia +4 more
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This article is published in Journal of Organic Chemistry.The article was published on 1991-04-01. It has received 870 citations till now. The article focuses on the topics: Lipase & Candida rugosa.read more
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Erkennung von Diastereomeren anhand ihrer Molekülgestalt durch NMR‐Spektroskopie in einem chiralen flüssigkristallinen Lösungsmittel
TL;DR: In this paper, eine eindeutige Zuordnung der Signale einzelner Diastereomere in nichtracemischen Mischungen gelingt durch 1H-entkoppelte 2H-NMR-Spektroskopie in chiralen, flussigkristallinen Losungsmitteln.
Journal ArticleDOI
Modification and simulation of Rhizomucor miehei lipase: the influence of surficial electrostatic interaction on enantioselectivity
TL;DR: Interaction analysis of transition state complexes of Rhizomucor miehei lipase and (R)- or (S)-n-butyl 2-phenxypropinate suggested an Asp61–Arg86 electrostatic interaction linking the loop and helix strongly impacting enantioselectivity of RmL.
Journal ArticleDOI
Biokatalytische Synthesen tertiärer Alkohole
TL;DR: A survey of the biocatalytic methods for the synthesis of (chiral) tertiary alcohols is presented in this paper, where advantages and disadvantages of the respective methods are discussed from a synthetic point of view.
Book ChapterDOI
Applications of Ionic Liquids to Increase the Efficiency of Lipase Biocatalysis
TL;DR: In the last decades, the utilization of new enzyme carriers was, besides exploitation of the increasing knowledge regarding enzyme structure and mechanism, the most important scientific trend in enzyme engineering.