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Proceedings ArticleDOI

A sequential method for measuring the optical properties of two-layer media with spatially-resolved diffuse reflectance: simulation study

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TLDR
In this paper, a sequential method for estimating the optical properties of two-layer media with spatially-resolved diffuse reflectance was proposed and validated using Monte Carlo generated reflectance profiles.
Abstract
A sequential method for estimating the optical properties of two-layer media with spatially-resolved diffuse reflectance was proposed and validated using Monte Carlo-generated reflectance profiles. The relationship between the penetration depth of detected photons and source-detector separation was first studied. Photons detected at larger source-detector separations generally penetrated deeper into the medium than those detected at small source-detector separations. The effect of each parameter (i.e., the absorption and reduced scattering coefficients (μa and μs′) of each layer, and the thickness of top layer) on reflectance was investigated. It was found that the relationship between the optical properties and thickness of top layer was a critical factor in determining whether photons would have sufficient interactions with the top layer and also penetrate into the bottom layer. The constraints for the proposed sequential estimation method were quantitatively determined by the curve fitting procedure coupled with error contour map analyses. Results showed that the optical properties of top layer could be determined within 10% error using the semi-infinite diffusion model for reflectance profiles with properly selected start and end points, when the thickness of top layer was larger than two times its mean free path (mfp’). And the optical properties of the bottom layer could be estimated within 10% error by the two-layer diffusion model, when the thickness of top layer was less than 16 times its mfp’. The proposed sequential estimation method is promising for improving the estimation of the optical properties of two-layer tissues from the same spatially-resolved reflectance.

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Citations
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Optimization of the hyperspectral imaging-based spatially-resolved system for measuring the optical properties of biological materials

TL;DR: In this paper, a hyperspectral imaging-based spatially-resolved system for determination of the optical properties of biological materials over the wavelengths of 500-1,000 nm is presented.
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Quality Assessment of Fruits and Vegetables Based on Spatially Resolved Spectroscopy: A Review

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Proceedings ArticleDOI

Influence of cost functions and optimization methods on solving the inverse problem in spatially resolved diffuse reflectance spectroscopy

TL;DR: In this article, a comparative numerical study of the performances in estimating OP depending on the choice made for each of the latter components is presented, and the combination between the number of variables to be estimated, the nature of the forward model, the cost function and the optimization method are discussed.
References
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MCML-Monte Carlo modeling of light transport in multi-layered tissues

Wang, +2 more
TL;DR: A Monte Carlo model of steady-state light transport in multi-layered tissues (MCML) has been coded in ANSI Standard C; therefore, the program can be used on various computers and has been in the public domain since 1992.
Journal ArticleDOI

MCML—Monte Carlo modeling of light transport in multi-layered tissues

TL;DR: A Monte Carlo model of steady-state light transport in multi-layered tissues (MCML) has been coded in ANSI Standard C; therefore, the program can be used on various computers as mentioned in this paper.
Journal ArticleDOI

A diffusion theory model of spatially resolved, steady-state diffuse reflectance for the noninvasive determination of tissue optical properties in vivo

TL;DR: A model based upon steady-state diffusion theory which describes the radial dependence of diffuse reflectance of light from tissues is developed and the optical properties derived for the phantoms are within 5%-10% of those determined by other established techniques.
BookDOI

Optical-Thermal Response of Laser-Irradiated Tissue

TL;DR: Welch et al. as discussed by the authors proposed a Monte Carlo Modeling of Light Transport in Tissue S.C. van Gemert, A.J. van Leeuwen, et al., and C.C., Svaasand.
Journal ArticleDOI

Improved solutions of the steady-state and the time-resolved diffusion equations for reflectance from a semi-infinite turbid medium

TL;DR: The error in deriving the optical coefficients is considerably smaller for the solutions under study than for the commonly used solutions, and analysis of experimental measurements of absolute steady-state spatially resolved reflectance confirms these results.
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