Journal ArticleDOI
Albumin-based nanoparticles as potential controlled release drug delivery systems.
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TLDR
The current review embodies an in-depth discussion of albumin nanoparticles with respect to types, formulation aspects, major outcomes of in vitro and in vivo investigations as well as site-specific drug targeting using various ligands modifying the surface of albumins with special insights to the field of oncology.About:
This article is published in Journal of Controlled Release.The article was published on 2012-01-30. It has received 1141 citations till now. The article focuses on the topics: Drug delivery & Drug carrier.read more
Citations
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Engineered Nanoparticles for Drug Delivery in Cancer Therapy
TL;DR: It is anticipated that precisely engineered nanoparticles will emerge as the next-generation platform for cancer therapy and many other biomedical applications.
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Controlled drug delivery vehicles for cancer treatment and their performance.
TL;DR: The different types of materials used as delivery vehicles for chemotherapeutic agents and their structural characteristics that improve the therapeutic efficacy of their drugs are discussed and recent scientific advances in the area of chemotherapy are described.
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Nanochemistry and Nanomedicine for Nanoparticle-based Diagnostics and Therapy
TL;DR: This work presents a new generation of high-performance liquid chromatography platforms for selective separation of Na6(CO3) from Na4(SO4) through Na2SO4 and shows real-world applications in drug discovery and treatment of central nervous system disorders.
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Intelligent Albumin-MnO2 Nanoparticles as pH-/H2 O2 -Responsive Dissociable Nanocarriers to Modulate Tumor Hypoxia for Effective Combination Therapy.
TL;DR: A unique type of pH/H2 O2 dual-responsive intelligent nanoscale delivery system based on albumin-coated MnO2 is presented, which is capable of modulating the tumor microenvironment by relieving hypoxia.
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Curcumin nanoformulations : A review of pharmaceutical properties and preclinical studies and clinical data related to cancer treatment
TL;DR: Recent works on the design and development of nano-sized delivery systems for curcumin, including liposomes, polymeric nanoparticles and micelles, conjugates, peptide carriers, cyclodextrins, solid dispersions, lipid nanoparticlesand emulsions are summarized.
References
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Electrospinning: Applications in drug delivery and tissue engineering
TL;DR: This review summarizes the most recent and state of the art work in electrospinning and its uses in tissue engineering and drug delivery and its ability to fabricate fibers with diameters on the nanometer size scale.
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Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles.
TL;DR: This review gives an account of the different drug delivery systems which make use of albumin as a drug carrier with a focus on those systems that have reached an advanced stage of preclinical evaluation or that have entered clinical trials.
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Use of electrospinning technique for biomedical applications
TL;DR: The importance of electrospinning for biomedical applications like tissue engineering drug release, wound dressing, enzyme immobilization etc. is highlighted in this paper, where the focus is also on the types of materials that have been electrospun.
Journal Article
The characterization of two specific drug binding sites on human serum albumin.
TL;DR: The binding of a number of fluorescent probe molecules to human serum albumin has been studied and changes in probe fluorescence were shown to be a result of competitive displacement by drugs.
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Polysaccharides-based nanoparticles as drug delivery systems
TL;DR: In this review, four mechanisms are introduced to prepare polysaccharides-based nanoparticles, that is, covalent crosslinking, ionic crossl linking, polyelectrolyte complex, and the self-assembly of hydrophobically modified poly Saccharides.