Journal ArticleDOI
Albumin microspheres and microcapsules: Methodology of manufacturing techniques
TLDR
In this paper, a methodological review of the preparation of albumin nano/microspheres and nano-microcapsules by suspension crosslinking is presented, and the dependence of microcapsule characteristics, namely hydration, biodegradability and core release, are also outlined.About:
This article is published in Journal of Controlled Release.The article was published on 1990-10-01. It has received 141 citations till now. The article focuses on the topics: Particle size.read more
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Glutaraldehyde as a fixative in bioprostheses and drug delivery matrices.
TL;DR: The chemistry of glutaraldehyde cross-linking and its effect on the biological performance of a number of bioprostheses such as tissue heart valves, vascular grafts, pericardial patches, tendon grafts and drug delivery matrices are examined.
Journal ArticleDOI
Preparation of Poly(methylmethacrylate) Microcapsules with Liquid Cores
Andrew Loxley,Brian Vincent +1 more
TL;DR: Particles with liquid cores and solid shells have been prepared by the controlled phase separation of poly(methylmethacrylate) (PMMA) within the droplets of an oil-in-water emulsion, finding that core/shell microcapsules were formed when hexadecane or decane was used as non-solvent and only when polymeric emulsifiers were employed.
Journal ArticleDOI
Microspheres of corn protein, zein, for an ivermectin drug delivery system
TL;DR: The results show that the zein microspheres and tablettedmicrospheres are suitable for use as a sustained-release form of IVM, implying a potential application in tissue engineering for preparing scaffold, which is composed of micro spheres encapsulating bioactive components for stimulating cell differentiation and proliferation.
Journal ArticleDOI
Preparation of biodegradable microspheres and microcapsules: 2. Polyactides and related polyesters
TL;DR: A general survey of the manufacturing methods of microspheres and microcapsules based on biodegradable polyesters, including polylactides, polyglycolide, polyhydroxybutyrate, polycaprolactone, polycarbonates and related copolymers is presented in this paper.
Journal ArticleDOI
A Hyaluronic Acid−Taxol Antitumor Bioconjugate Targeted to Cancer Cells
TL;DR: The notion that the targeted cytotoxicity of HA-Taxol bioconjugates requires receptor-mediated cellular uptake of theBioconjugate followed by hydrolytic release of free Taxol is supported.
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Journal ArticleDOI
Magnetic Microspheres: Synthesis of a Novel Parenteral Drug Carrier
TL;DR: The synthesis and characterization of a novel parenteral drug carrier capable of area specific localization by magnetic means and release doxorubicin was chemically identical to the starting material.
Journal Article
Albumin Microspheres for Study of the Reticuloendothelial System
TL;DR: In this article, an improved method for the preparation of HSA microspheres with an average diameter of 0.5-0.7 microns and narrow particle-size range, suitable for the study of the RES, has been described.
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Albumin Microspheres as Vehicles for Achieving Specificity in Drug Delivery
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Preparation of hydrophilic albumin microspheres using polymeric dispersing agents.
TL;DR: In this paper, a new method for preparing glutaraldehyde crosslinked human serum albumin microspheres has been developed, which includes the addition of glutarsaldehyde in the organic phase and use of concentrated solutions of hydrophobic polymers (polymethylmethacrylate) or hydrophilic polymers as dispersion media.