Journal ArticleDOI
An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets
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TLDR
This paper provides a powerful method of probing fMRI data using automatically generated masks based on lobar anatomy, cortical and subcortical anatomy, and Brodmann areas based on an automated atlas-based masking technique.About:
This article is published in NeuroImage.The article was published on 2003-07-01. It has received 4998 citations till now.read more
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Impact of a microRNA MIR137 susceptibility variant on brain function in people at high genetic risk of schizophrenia or bipolar disorder
Heather C. Whalley,Martina Papmeyer,Liana Romaniuk,Emma Sprooten,Eve C. Johnstone,Jeremy Hall,Stephen M. Lawrie,Kathryn L. Evans,Hilary P. Blumberg,Jessika E. Sussmann,Andrew M. McIntosh +10 more
TL;DR: The results suggest that the newly identified SCZ locus may influence brain activation in a manner that is partly dependent on the presence of existing genetic susceptibility for SCZ.
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White matter changes in preclinical Alzheimer's disease: A magnetic resonance imaging-diffusion tensor imaging study on cognitively normal older people with positive amyloid β protein 42 levels
José Luis Molinuevo,Pablo Ripollés,Marta Simó,Albert Lladó,Jaume Olives,Mircea Balasa,Anna Antonell,Antoni Rodríguez-Fornells,Antoni Rodríguez-Fornells,Lorena Rami +9 more
TL;DR: The finding of AxD alteration together with preserved fractional anisotropy, mean diffusivity, and radialdiffusivity indexes in the CN_Aβ42+ group may indicate that, subtle axonal changes may be happening in the preclinical phases of Alzheimer's disease, whereas white matter integrity is still widely preserved.
Journal ArticleDOI
Fronto-striatal deficit in Parkinson's disease during semantic event sequencing.
TL;DR: This study examined early-stage, nondemented, medicated PD subjects and matched control subjects during a semantic event sequencing task using functional MRI, and found abnormal activation within the prefrontal cortex (PFC) and the "default" network in the PD group.
Journal ArticleDOI
Functional imaging of emotional memory in bipolar disorder and schizophrenia
Heather C. Whalley,James McKirdy,Liana Romaniuk,Jessika E. Sussmann,Eve C. Johnstone,Hong I Wan,Andrew M. McIntosh,Stephen M. Lawrie,Jeremy Hall +8 more
TL;DR: Evidence is provided that there are distinct patterns of activation in the MTL during an emotional memory task in bipolar disorder and schizophrenia and that different mood states are associated with different neurobiological responses to emotion across the patient groups.
Journal ArticleDOI
Neuroanatomical correlates of neurological soft signs in antipsychotic-naive schizophrenia
Ganesan Venkatasubramanian,Peruvumba N. Jayakumar,Bangalore N. Gangadhar,Matcheri S. Keshavan +3 more
TL;DR: In this article, the authors examined gray matter volume correlates of neurological soft signs (NSS) in antipsychotic-naive schizophrenia patients using an automated image analysis technique and found that the MSS sub-score had a significant negative correlation with total and regional gray matter volumes (prefrontal, posterior cingulate, temporal cortices, putamen, and cerebellum).
References
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Journal ArticleDOI
Statistical parametric maps in functional imaging: A general linear approach
Karl J. Friston,Andrew P. Holmes,Keith J. Worsley,J-B. Poline,Chris D. Frith,Richard S. J. Frackowiak +5 more
TL;DR: In this paper, the authors present a general approach that accommodates most forms of experimental layout and ensuing analysis (designed experiments with fixed effects for factors, covariates and interaction of factors).
Book
Co-planar stereotaxic atlas of the human brain : 3-dimensional proportional system : an approach to cerebral imaging
TL;DR: Direct and Indirect Radiologic Localization Reference System: Basal Brain Line CA-CP Cerebral Structures in Three-Dimensional Space Practical Examples for the Use of the Atlas in Neuroradiologic Examinations Three- Dimensional Atlas of a Human Brain Nomenclature-Abbreviations Anatomic Index Conclusions.
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Spatial registration and normalization of images
Karl J. Friston,John Ashburner,Chris D. Frith,Jean-Baptiste Poline,Jon D. Heather,Richard S. J. Frackowiak +5 more
TL;DR: A general technique that facilitates nonlinear spatial (stereotactic) normalization and image realignment is presented that minimizes the sum of squares between two images following non linear spatial deformations and transformations of the voxel (intensity) values.
Journal ArticleDOI
Automated Talairach Atlas labels for functional brain mapping
Jack L. Lancaster,Marty G. Woldorff,Lawrence M. Parsons,Mario Liotti,Catarina S. Freitas,Lacy Rainey,Peter Kochunov,D. S. Nickerson,Shawn A. Mikiten,Peter T. Fox +9 more
TL;DR: When used in concert with authors' deeper knowledge of an experiment, the TD system provides consistent and comprehensive labels for brain activation foci, which is better than that of the expert group.
Journal ArticleDOI
Automatic 3-D model-based neuroanatomical segmentation
TL;DR: A 3‐D model‐based segmentation method is presented in this paper for the completely automatic identification and delineation of gross anatomical structures of the human brain based on their appearance in magnetic resonance images (MRI).