Journal ArticleDOI
An Efficient Rhodium‐Catalyzed Double Hydroaminocarbonylation of Alkynes with Carbon Monoxide and Amines Affording 1,4‐Diamide Derivatives
Qiufeng Huang,Ruimao Hua +1 more
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TLDR
The hydroaminocarbonylation of terminal alkynes with carbon monoxide and pyrrolidine or piperidine catalyzed by rhodium complexes affords 1,4-diamide derivatives in good to high yields as mentioned in this paper.Abstract:
The hydroaminocarbonylation of terminal alkynes with carbon monoxide and pyrrolidine or piperidine catalyzed by rhodium complexes affords 1,4-diamide derivatives in good to high yields.read more
Citations
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Metal-catalysed approaches to amide bond formation
TL;DR: In this tutorial review, highlights of the recent literature have been presented covering the key areas where metal catalysts have been used in amide bond formation.
Journal ArticleDOI
Nonclassical Routes for Amide Bond Formation
TL;DR: The present review offers an overview of nonclassical (e.g., with no pre- or in situ activation of a carboxylic acid partner) approaches for the construction of amide bonds.
Journal ArticleDOI
Synthesis of isoquinolines and heterocycle-fused pyridines via three-component cascade reaction of aryl ketones, hydroxylamine, and alkynes.
TL;DR: An efficient one-pot synthesis of isoquinolines and heterocycle-fused pyridines by three-component reaction of aryl ketones, hydroxylamine, and alkynes is developed.
Journal ArticleDOI
Highly Ligand-Controlled Regioselective Pd-Catalyzed Aminocarbonylation of Styrenes with Aminophenols
Tongyu Xu,Feng Sha,Howard Alper +2 more
TL;DR: Ligand-controlled regioselective Pd-catalyzed carbonylation of styrenes with aminophenols was realized, chemoselectively affording amides and studies on the acid additives show that different acids act as the proton source and the corresponding counterion can help enhance the reactivity and selectivity.
Journal ArticleDOI
Rh(I)-Catalyzed Hydroamidation of Olefins via Selective Activation of N–H Bonds in Aliphatic Amines
TL;DR: Mechanistic studies reveal the presence of Rh-acyl species as crucial intermediates for the selectivity and rate-limiting step in the proposed Rh(I)-catalytic cycle.
References
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Ruthenium in organic synthesis
TL;DR: In this paper, the authors present a list of contributors to the work of Murahashi and Noyori on dehydrogenative Oxidation with Ruthenium complex catalysts and Oxidants.
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Regioselective Palladium(II)-Catalyzed Synthesis of Five- or Seven-Membered Ring Lactones and Five-, Six- or Seven-Membered Ring Lactams by Cyclocarbonylation Methodology
TL;DR: In this paper, the reaction of 2-allylanilines with CO/H2 using the catalytic system Pd(OAc)2/PPh3, while use of 1,4-bis(diphenylphosphino)butane instead of PPh3 in the latter process results in the formation of the seven-membered ring lactams benzazepinones in good yield.
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Ru-catalyzed anti-Markovnikov addition of amides to alkynes: A regio- and stereoselective synthesis of enamides
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Dodecacarbonyltriruthenium catalysed carbonylation of amines and hydroamidation of olefins
TL;DR: In this article, Dodecacarbonyltriruthenium (Ru 3 (CO) 12 ) is an effective homogeneous catalyst precursor for the carbonylation of amines and hydroamidation of olefins under a carbon monoxide pressure of 40 kg cm −2 at 120 −180°C.