Journal ArticleDOI
An RNA-Dependent DNA Polymerase in Virions of Rous Sarcoma Virus
Satoshi Mizutani,Howard M. Temin +1 more
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This article is published in Cold Spring Harbor Symposia on Quantitative Biology.The article was published on 1970-01-01. It has received 590 citations till now. The article focuses on the topics: Rous sarcoma virus & RNA-dependent RNA polymerase.read more
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Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase.
Louis M. Mansky,Howard M. Temin +1 more
TL;DR: In vivo mutation rates for HIV-1 are three and seven times higher than those previously reported for two other retroviruses, spleen necrosis virus and bovine leukemia virus, respectively, and the calculated in vivo mutation rate is about 20-fold lower than the error rate of purified HIV- 1 reverse transcriptase, with the same target sequence.
Journal ArticleDOI
The general transcription machinery and general cofactors.
Mary C. Thomas,Cheng Ming Chiang +1 more
TL;DR: These cofactors are capable of repressing basal transcription when activators are absent and stimulating transcription in the presence of activators, with emphasis on the events occurring after the chromatin has been remodeled but prior to the formation of the first phosphodiester bond.
Journal ArticleDOI
Expression of Animal Virus Genomes
TL;DR: A scheme is presented and the behavior of three viral systems which have been investigated in my laboratory are discussed and some of the implications of the existence of these viral systems in the context of thebehavior of normal cells are discussed.
Journal ArticleDOI
Why do viruses cause cancer? Highlights of the first century of human tumour virology
Patrick S. Moore,Yuan Chang +1 more
TL;DR: A diverse group of viruses reveals unexpected connections between innate immunity, immune sensors and tumour suppressor signalling that control both viral infection and cancer.
BookDOI
Human tumor cells in vitro
TL;DR: The strategy of a Search for Viral Involvement in Human Cancer and Helper Activity for the Defective Friend Leukemia Virus in Human Malignant Cell Cultures are considered.
Related Papers (5)
Complementarity between Rous sarcoma virus (RSV) RNA and the in vitro-synthesized DNA of the virus-associated DNA polymerase.
Peter H. Duesberg,E. Canaani +1 more