Journal ArticleDOI
Anti-TNF-α therapy in refractory uveitis associated with sarcoidosis: Multicenter study of 17 patients.
Leyre Riancho-Zarrabeitia,Vanesa Calvo-Río,Ricardo Blanco,Marina Mesquida,Alfredo Adán,José M. Herreras,Angel Garcia Aparicio,Diana Peiteado-Lopez,Miguel Cordero-Coma,José Luis García Serrano,Norberto Ortego-Centeno,O. Maíz,Ana Blanco,Juan Sánchez-Bursón,Senén González-Suárez,Alejandro Fonollosa,Montserrat Santos-Gómez,Carmen González-Vela,Javier Loricera,Trinitario Pina,Miguel A. González-Gay +20 more
TLDR
Anti-TNF-α therapy is effective in sarcoid uveitis patients refractory to conventional immunosuppressive therapy and a substantial reduction in prednisone dose despite having failed standard therapy is observed.About:
This article is published in Seminars in Arthritis and Rheumatism.The article was published on 2015-12-01. It has received 65 citations till now. The article focuses on the topics: Infliximab & Prednisone.read more
Citations
More filters
Journal ArticleDOI
Anti-Interleukin-6 Receptor Tocilizumab for Severe Juvenile Idiopathic Arthritis-Associated Uveitis Refractory to Anti-Tumor Necrosis Factor Therapy: A Multicenter Study of Twenty-Five Patients.
Vanesa Calvo-Río,Montserrat Santos-Gómez,Inmaculada Calvo,M. Isabel González-Fernández,Berta López-Montesinos,Marina Mesquida,Alfredo Adán,Maria Victoria Hernández,O. Maíz,Antonio Atanes,B. Bravo,Consuelo Modesto,Gisela Díaz-Cordovés,Natalia Palmou-Fontana,Javier Loricera,María Carmen González-Vela,R. Demetrio-Pablo,José L. Hernández,Miguel A. González-Gay,Ricardo Blanco +19 more
TL;DR: In this article, the authors conducted a multicenter study of patients with JIA-associated uveitis that was refractory to conventional immunosuppressive drugs and anti-tumor necrosis factor (anti-TNF) agents.
Journal ArticleDOI
Anti-interleukin 6 receptor tocilizumab in refractory uveitis associated with Behçet's disease: multicentre retrospective study.
Belén Atienza-Mateo,Vanesa Calvo-Río,Emma Beltrán,Lucía Martínez-Costa,Elia Valls-Pascual,Marisa Hernández-Garfella,Antonio Atanes,Miguel Cordero-Coma,Joan M. Nolla,Carmen Carrasco-Cubero,Javier Loricera,María Carmen González-Vela,N. Vegas-Revenga,C. Fernández-Díaz,R. Demetrio-Pablo,L Domínguez-Casas,José Luis Martín-Varillas,Natalia Palmou-Fontana,José L. Hernández,Miguel A. González-Gay,Ricardo Blanco +20 more
TL;DR: TCZ yielded rapid and maintained improvement in all ocular parameters of the patients, with complete remission in eight of them, but this was not the case for the extraocular manifestations, since TCZ was only effective in three of them.
Journal ArticleDOI
Comparative Study of Infliximab Versus Adalimumab in Refractory Uveitis due to Behçet's Disease: National Multicenter Study of 177 Cases.
Belén Atienza‐Mateo,José Luis Martín‐Varillas,Vanesa Calvo-Río,R. Demetrio-Pablo,Emma Beltrán,Juan Sanchez-Burson,Marina Mesquida,Alfredo Adán,Maria Victoria Hernández,Marisa Hernández-Garfella,Elia Valls-Pascual,Lucia Martinez-Costa,Agustí Sellas‐Fernández,Miguel Cordero-Coma,Manuel Diaz-Llopis,Roberto Gallego,José L. García‐Serrano,Norberto Ortego-Centeno,Jose M. Herreras,Alejandro Fonollosa,Angel Garcia-Aparicio,Olga Maíz‐Alonso,Ana Blanco,Ignacio Torre-Salaberri,Cruz Fernandez-Espartero,Vega Jovaní,Diana Peiteado,Esperanza Pato,Juan Mendózar Cruz,Carlos Férnandez-Cid,Elena Aurrecoechea,Miriam García-Arias,Santos Castañeda,Miguel A. Caracuel‐Ruiz,Carlos A. Montilla‐Morales,Antonio Atanes-Sandoval,Félix Francisco,Santos Insua,Senen González-Suárez,A. Sanchez-Andrade,Fernando Gamero,Luis F. Linares Ferrando,F. Romero‐Bueno,A. Javier García-González,Raquel Almodóvar González,Enrique Minguez Muro,Carmen Carrasco‐Cubero,Alejandro Olivé,Águeda Prior,Julio Vázquez,Oscar Ruiz-Moreno,Fernando Jiménez-Zorzo,Javier Manero,Santiago Muñoz Fernandez,Cristina Fernández‐Carballido,Esteban Rubio-Romero,Fred Antón Pages,Francisco J. Toyos‐Sáenz de Miera,Myriam Gandia Martinez,David Díaz-Valle,Francisco Javier Lopez Longo,Joan M. Nolla,Enrique Raya Álvarez,Marcelino Revenga Martinez,Julio J. González-López,Paz Rodríguez‐Cundin,José L. Hernández,Miguel A. González-Gay,Ricardo Blanco +68 more
TL;DR: To compare the efficacy of infliximab (IFX) versus adalimumab (ADA) as a first‐line biologic drug over 1 year of treatment in a large series of patients with refractory uveitis due to Behçet's disease (BD).
Journal ArticleDOI
Anti-IL6-Receptor Tocilizumab in Refractory and Noninfectious Uveitic Cystoid Macular Edema: Multicenter Study of 25 Patients.
N. Vegas-Revenga,Vanesa Calvo-Río,Marina Mesquida,Alfredo Adán,Maria Victoria Hernández,Emma Beltrán,Elia Valls Pascual,David Díaz-Valle,Gisela Díaz-Cordovés,Marisa Hernández-Garfella,Lucía Martínez-Costa,Inmaculada Calvo,Antonio Atanes,L. Linares,Consuelo Modesto,Carmen González-Vela,R. Demetrio-Pablo,Elena Aurrecoechea,Miguel Cordero,L Domínguez-Casas,Belén Atienza-Mateo,José Luis Martín-Varillas,Javier Loricera,Natalia Palmou-Fontana,José L. Hernández,Miguel A. González-Gay,Ricardo Blanco +26 more
TL;DR: Macular thickness is reduced following administration of tocilizumab (TCZ) in refractory uveitis-related CME, a statistically significant improvement in macular thickness compared to baseline.
References
More filters
Journal ArticleDOI
Standardization of uveitis nomenclature for reporting clinical data. Results of the First International Workshop.
TL;DR: In this article, a process of standardizing the methods for reporting clinical data in the field of uveitis has been discussed, and the results used to develop a series of proposals to better standardize the use of these entities.
Journal ArticleDOI
Anti-TNF Antibody Therapy in Rheumatoid Arthritis and the Risk of Serious Infections and Malignancies: Systematic Review and Meta-analysis of Rare Harmful Effects in Randomized Controlled Trials
Tim Bongartz,Alex J. Sutton,Michael J. Sweeting,Iain Buchan,Eric L. Matteson,Victor M. Montori +5 more
TL;DR: There is evidence of an increased risk of serious infections and a dose-dependent increasedrisk of malignancies in patients with rheumatoid arthritis treated with anti-TNF antibody therapy.
Journal ArticleDOI
Clinical Characteristics of Patients in a Case Control Study of Sarcoidosis
Robert P. Baughman,Alvin S. Teirstein,Marc A. Judson,Milton D. Rossman,Henry Yeager,Eddy A. Bresnitz,Louis DePalo,Gary M. Hunninghake,Michael C. Iannuzzi,Carol J. Johns,Geoffrey McLennan,David R. Moller,Lee S. Newman,David L. Rabin,Cecile S. Rose,Benjamin A. Rybicki,Steven E. Weinberger,Michael L. Terrin,Genell L. Knatterud,Reuben Cherniak +19 more
TL;DR: It is concluded that the initial presentation of sarcoidosis is related to sex, race, and age.
Journal ArticleDOI
Infliximab therapy in patients with chronic sarcoidosis and pulmonary involvement.
Robert P. Baughman,Marjolein Drent,Mani S. Kavuru,Marc A. Judson,Ulrich Costabel,Roland M. du Bois,Carlo Albera,Martin Brutsche,Gerald S. Davis,James F. Donohue,Joachim Müller-Quernheim,Rozsa Schlenker-Herceg,Susan Flavin,Kim Hung Lo,Barry Oemar,Elliot S. Barnathan +15 more
TL;DR: The results of this Phase 2 clinical study support further evaluation of anti-TNF-alpha therapy in severe, chronic, symptomatic sarcoidosis.
Related Papers (5)
Adalimumab in Patients with Active Noninfectious Uveitis
Glenn J. Jaffe,Andrew D. Dick,Andrew D. Dick,Antoine P. Brézin,Quan Dong Nguyen,Jennifer E. Thorne,Philippe Kestelyn,Talin Barisani-Asenbauer,Pablo Franco,Arnd Heiligenhaus,David Scales,David S Chu,Anne Camez,Nisha V. Kwatra,Alexandra P. Song,Martina Kron,Samir R. Tari,Eric B. Suhler,Eric B. Suhler +18 more