Journal ArticleDOI
Anticancer cyclometalated complexes of platinum group metals and gold
Natalia Cutillas,Gorakh S. Yellol,Concepción de Haro,Consuelo Vicente,Venancio Rodríguez,José Ruiz +5 more
TLDR
A review of cyclometalated C N complexes and C N C, C N N and C n S pincer complexes of platinum, palladium, gold, ruthenium, rhodium, and iridium can be found in this article.About:
This article is published in Coordination Chemistry Reviews.The article was published on 2013-10-01. It has received 283 citations till now. The article focuses on the topics: Ruthenium & Rhodium.read more
Citations
More filters
Antitumour metal compounds: more than theme and variations
Michael A. Jakupec,Markus Galanski,Vladimir B. Arion,Christian G. Hartinger,Bernhard K. Keppler +4 more
TL;DR: The recent achievement of oxaliplatin for the treatment of colon cancer should not belie the imbalance between a plethora of investigated complexes and a very small number of clinically approved platinum drugs.
Journal ArticleDOI
Noble metals in medicine: Latest advances
Serenella Medici,Massimiliano Francesco Peana,Valeria Marina Nurchi,Joanna Izabela Lachowicz,Guido Crisponi,Maria Antonietta Zoroddu +5 more
TL;DR: A detailed account of the latest results of metal-based drugs and their potential uses in the cure of severe diseases is provided and the number of published studies in this field is huge.
Journal ArticleDOI
Supramolecular chemotherapy based on host–guest molecular recognition: a novel strategy in the battle against cancer with a bright future
Jiong Zhou,Guocan Yu,Feihe Huang +2 more
TL;DR: A review summarizing the progress of supramolecular chemotherapy in cancer treatment based on host-guest recognition and guidance on the design of new targeting supramolescular chemotherapy combining diagnostic and therapeutic functions is presented.
Journal ArticleDOI
Chemical biology of anticancer gold(III) and gold(I) complexes
TL;DR: The current understanding of anticancer gold complexes is summarized, including their mechanisms of action and the approaches adopted to improve their anticancer efficiency.
Journal ArticleDOI
Anti-cancer palladium complexes: a focus on PdX2L2, palladacycles and related complexes.
TL;DR: This review provides readers with an up to date account of the advances that have taken place over the past several decades in platinum-based chemotherapeutic agents, i.e. through interactions with DNA.
References
More filters
Journal ArticleDOI
Structure, Recognition, and Processing of Cisplatin-DNA Adducts.
Journal ArticleDOI
Targeting DNA topoisomerase II in cancer chemotherapy
TL;DR: These studies promise refined targeting of TOP2 as an effective anticancer strategy and the ability to interfere with TOP2 and generate enzyme-mediated DNA damage is an effective strategy for cancer chemotherapy.
Journal ArticleDOI
Organometallic Anticancer Compounds
TL;DR: The quest for alternative drugs to the well-known cisplatin and its derivatives, which are still used in more than 50% of the treatment regimes for patients suffering from cancer, is highly needed, and organometallic compounds have recently been found to be promising anticancer drug candidates.
BookDOI
Cisplatin : chemistry and biochemistry of a leading anticancer drug
TL;DR: The start: platinum complexes for the treatment of cancer - why the search goes on and new developments: structure-activity relationships within di- and trinuclear platinum phase I clinical anticancer agents the development of orally-active platinum drugs methods for screening the potential antitumor activity of platinum compounds in combinatorial libraries computational studies on platinum antitumors complexes and their adducts with nucleid acids constituents.