Journal ArticleDOI
Antihepatotoxic activity of Swertia chirata on carbon tetrachloride induced hepatotoxicity in rats
Reads0
Chats0
TLDR
The methanol extract of Swertia chirata was evaluated for antihepatotoxic activity against carbon tetrachloride induced liver toxicity in experimental rats and was found to be active and on fractionation into butanol soluble and chloroform soluble fractions, the activity was traced and found more profound in the chloro Form soluble fraction.Abstract:
The methanol extract of Swertia chirata was evaluated for antihepatotoxic activity against carbon tetrachloride induced liver toxicity in experimental rats. The extract was found to be active and on fractionation into butanol soluble and chloroform soluble fractions, the activity was traced and found more profound in the chloroform soluble fraction. The butanol soluble bitter rich fraction showed marginal activity. The results based on biochemical estimations have been expressed statistically and are additionally supported by histopathological examination of the liver of experimental rats and pentobarbitone induced sleep time studies in mice.read more
Citations
More filters
Journal Article
Hepatoprotective Activity of Methanol Extract of Some Medicinal Plants Against Carbon Tetrachloride Induced Hepatotoxicity in Albino Rats
TL;DR: The extracts of four above plants could afford significant dose-dependent protection against CCl induced hepatocellular injury and this activity was supported by histopathological studies of liver tissue.
Journal ArticleDOI
Hepatoprotective and antioxidant effects of licorice extract against CCl₄-induced oxidative damage in rats.
TL;DR: The data of this study support a chemopreventive potential of licorice extract against liver oxidative injury and significantly reverses the increased liver hydroxyproline and serum TNF-α levels induced by CCl4 intoxication.
Journal ArticleDOI
Hepatoprotective effect of Vitis vinifera L. leaves on carbon tetrachloride-induced acute liver damage in rats
TL;DR: The hepatoprotective effect of ethanolic extract and its four different fractions of Vitis vinifera L. leaves was investigated against carbon tetrachloride-induced acute hepatotoxicity in rats and Legalon 70 Protect was used as standard natural originated drug.
Journal ArticleDOI
In vitro antimalarial activity of extracts of three plants used in the traditional medicine of India.
TL;DR: Among the 3 plants tested, 2 had significant inhibitory effect on P. falciparum in vitro, and the value that inhibits 50% (IC50) was determined.
Journal ArticleDOI
Swertia (Gentianaceae): chemical and pharmacological aspects.
Goutam Brahmachari,Sadhan Mondal,Arindam Gangopadhyay,Dilip Gorai,Bodhiswatta Mukhopadhyay,Shamal Saha,Arun K. Brahmachari +6 more
TL;DR: The botanical classification and ethno‐pharmacology of Swertia plants, as well as the biological activities and pharmacological applications of both distinct phytochemicals and medicinally acitve plant materials (formulations, extracts, etc.) are discussed in detail.
References
More filters
Book
Remington's pharmaceutical sciences
TL;DR: The 17th edition of Remington's pharmaceutical sciences is organized as its immediate predecessors, adhering to the concept of division into 9 parts, each subdivided into several chapters as mentioned in this paper.
Journal ArticleDOI
A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases.
Stanley Reitman,Sam Frankel +1 more
Remington's pharmaceutical sciences
TL;DR: The 17th edition of Remington's pharmaceutical sciences is organized as its immediate predecessors, adhering to the concept of division into 9 parts, each subdivided into several chapters, with an actual physical increase of fewer that 100 pages.
Journal ArticleDOI
Estimation of Plasma Phosphatase by Determination of Hydrolysed Phenol with Amino-antipyrine
P. R. N. Kind,E. J. King +1 more
TL;DR: The conditions under which enzymic hydrolysis is carried out are the same as in the King-Armstrong method, as modified by King (1951), the amino-antipyrine reagent (A.A.P.) being used to estimate the phenol liberated.