Antimicrobial activities of silver dressings: an in vitro comparison.
TLDR
Understanding the characteristics of silver-coated or -impregnated dressings may enable them to be targeted more appropriately according to the specific requirements for use of a particular dressing, as in for prophylaxis in skin grafting or for an infected wound with MRSA.Abstract:
A range of silver-coated or -impregnated dressings are now commercially available for use but comparative data on their antimicrobial efficacies are limited. The antibacterial activities of five commercially available silver-coated/impregnated dressings were compared against nine common burn-wound pathogens, namely methicillin-sensitive and -resistant Staphylococcus aureus (MRSA), Enterococcus faecalis, Pseudomonas aeruginosa, Escherichia coli, Enterobacter cloacae, Proteus vulgaris, Acinetobacter baumannii and a multi-drug-efflux-positive Acinetobacter baumannii (BM4454), using a broth culture method. The rapidity and extent of killing of these pathogens under in vitro conditions were evaluated. All five silver-impregnated dressings investigated exerted bactericidal activity, particularly against Gram-negative bacteria, including Enterobacter species, Proteus species and E. coli. The spectrum and rapidity of action, however, ranged widely for different dressings. Acticoat and Contreet had a broad spectrum of bactericidal activities against both Gram-positive and -negative bacteria. Contreet was characterized by a very rapid bactericidal action and achieved a reduction of > or =10,000 c.f.u. ml(-1) in the first 30 min for Enterobacter cloacae, Proteus vulgaris, Pseudomonas aeruginosa and Acinetobacter baumanii. Other dressings demonstrated a narrower range of bactericidal activities. Understanding the characteristics of these dressings may enable them to be targeted more appropriately according to the specific requirements for use of a particular dressing, as in for prophylaxis in skin grafting or for an infected wound with MRSA.read more
Citations
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Environmental Chemistry DIFFERENTIAL SENSITIVITY OF NITRIFYING BACTERIA TO SILVER NANOPARTICLES IN ACTIVATED SLUDGE
TL;DR: In this paper, the impact of AgNPs and their released silver ions (Ag þ ) on the abundance, activity, and diversity of different nitrifying bacteria in wastewater treatment plants (WWTPs) was investigated.
Dissertation
Polymerní biomateriály pro medicinální aplikace
TL;DR: The practical part of this work deals with the study of selected commercially available products used as wound dressing, which contain antibacterial substance - silver, which was determined by the methods ED - XRF and AAS.
Journal Article
Evaluation of antimicrobial activity of silver nanoparticle using Eichhornia crassipes leaves extract
AS Prabakaran,N Mani +1 more
TL;DR: The results of this study clearly indicate that silver nanoparticles synthesized from plant extract of Eichhornia crassipes has many pharmaceutical applications for the control of deadly pathogens.
References
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Journal ArticleDOI
Bacterial silver resistance: molecular biology and uses and misuses of silver compounds
TL;DR: Resistance to silver compounds as determined by bacterial plasmids and genes has been defined by molecular genetics and the use of molecular epidemiological tools will establish the range and diversity of such resistance systems in clinical and non-clinical sources.
Journal ArticleDOI
Silver-based crystalline nanoparticles, microbially fabricated
TL;DR: Transmission electron microscopy, quantitative energy-dispersive x-ray analysis, and electron diffraction established that the crystals comprise at least three different types, found both in whole cells and thin sections, in Pseudomonas stutzeri AG259.
Journal ArticleDOI
Silver nanoparticles and polymeric medical devices: a new approach to prevention of infection?
Franck Furno,Kelly S. Morley,Ben Wong,Barry L. Sharp,Polly L. Arnold,Steven M. Howdle,Roger Bayston,Paul D. Brown,Peter D. Winship,Helen J. Reid +9 more
TL;DR: A completely new approach using supercritical carbon dioxide to impregnate silicone with nanoparticulate silver metal allows for the first time silver impregnation of medical polymers and promises to lead to an antimicrobial biomaterial whose activity is not restricted by increasing antibiotic resistance.
Journal ArticleDOI
Silver. I: Its antibacterial properties and mechanism of action.
TL;DR: The main mechanism of action of silver products, which are broad-spectrum antibiotics and are not yet associated with drug resistance, is described.
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