Journal ArticleDOI
Binding of mercury in the rat kidney by metallothionein
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TLDR
Metallothionein is identified as the compound responsible for the selective binding and retention of mercury in the kidney of rats.About:
This article is published in Toxicology and Applied Pharmacology.The article was published on 1970-05-01. It has received 107 citations till now. The article focuses on the topics: Metallothionein & Sephadex.read more
Citations
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Influence of a standard laboratory diet containing nutritionally adequate levels of selenium on renal pathology from mercury released by experimental amalgam tattoos
B.M. Eley,S.W. Cox +1 more
TL;DR: It would seem likely that the low Se levels present within this standard laboratory diet were sufficient to protect against Hg toxicity.
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Effect of mercury on tissue glutathione following intrarenal injection of mercuric chloride
K N Kee,Yoke Min Sin +1 more
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Protection by spironolactone and different antidotes against acute organic mercury poisoning of rats.
TL;DR: Investigations at the laboratory have shown that BAL (dimercaptopropanol) can be used, with some restrictions, in the treatment of organic mercury poisoning, and spironolactone proved to be effective in the case of MEMC when administered prior to poisoning.
Binding of Cadmium on Metallothionein in Man: An Analysis of a Fatal Poisoning by Cadmium Iodide*
Z. Mr,Received March +1 more
TL;DR: The data are suggestive that cadmium induced biosynthesis of metallothionein, and Cd-protein complexes in the body of a man fatally poisoned with CdJ~, after an oral dose of about 5 g are suggestive of the presence of these proteins in theorgan distribution.
Journal ArticleDOI
Behaviour of mercury in animals. I Distribution of mercury binding protein in the kidney and liver of mice exposed to HgCl2
TL;DR: In the mice repeatedly exposed, amount of mercury in the kidney increased in the low molecular weight fraction, but the distribution of mercury binding protein of the liver remained almost unchanged.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Estimation of the molecular weights of proteins by Sephadex gel-filtration.
TL;DR: The results are similar to those of previous studies, where the objective was to establish a cause-and-effect relationship, rather than a straightforward relationship between the number of cells and the content of the molecule.
Journal ArticleDOI
The gel-filtration behaviour of proteins related to their molecular weights over a wide range
TL;DR: Correlation between elution volume, V(e), and molecular weight was investigated for gel filtration of proteins of molecular weights ranging from 3500 (glucagon) to 820000 (alpha-crystallin) on Sephadex G-200 columns at pH7.5.