Journal ArticleDOI
Binding of mercury in the rat kidney by metallothionein
Reads0
Chats0
TLDR
Metallothionein is identified as the compound responsible for the selective binding and retention of mercury in the kidney of rats.About:
This article is published in Toxicology and Applied Pharmacology.The article was published on 1970-05-01. It has received 107 citations till now. The article focuses on the topics: Metallothionein & Sephadex.read more
Citations
More filters
Journal ArticleDOI
The aging kidney and the nephrotoxic effects of mercury.
TL;DR: Known findings related to exposure of aged and diseased kidneys to the environmentally relevant nephrotoxicant Hg are summarized to summarize.
Journal ArticleDOI
Binding of cadmium and mercury by metallothionein in the kidneys and liver of rats following repeated administration
TL;DR: Rats were injected subcutaneously with either cadmium chloride or mercuric chloride every other day over a period of 6 to 7 weeks to determine levels of metals and metallothionein in liver and kidneys.
Journal ArticleDOI
Binding of mercury and selenium in subcellular fractions of rat liver and kidneys following separate and joint administration.
TL;DR: The distribution of mercury and selenium has been examined in subcellular fractions of rat liver and kidneys in prolonged exposure to HgCl2 and Na2SeO3 administered separately and simultaneously.
Journal ArticleDOI
Studies on the uptake of cadmium by the crab Carcinus maenas in the laboratory. II. Preliminary investigation of cadmium-binding proteins
TL;DR: A tentative model of the fate of water-soluble Cadmium absorbed by the crab is proposed and two proteins with a high affinity for cadmium have been found with molecular weights of approximately 12,000 and 27,000.
Journal ArticleDOI
Changes in mercury levels in harbor porpoises from the Bay of Fundy, Canada, and adjacent waters during 1969-1977.
TL;DR: It is speculated that the decline in Hg levels could be correlated with a dominance of relatively mercury-poor Gulf Stream water in the Bay of Fundy approaches in 1971–73, as opposed to the usual dominance by waters of the Nova Scotia current.
References
More filters
Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Estimation of the molecular weights of proteins by Sephadex gel-filtration.
TL;DR: The results are similar to those of previous studies, where the objective was to establish a cause-and-effect relationship, rather than a straightforward relationship between the number of cells and the content of the molecule.
Journal ArticleDOI
The gel-filtration behaviour of proteins related to their molecular weights over a wide range
TL;DR: Correlation between elution volume, V(e), and molecular weight was investigated for gel filtration of proteins of molecular weights ranging from 3500 (glucagon) to 820000 (alpha-crystallin) on Sephadex G-200 columns at pH7.5.