Journal ArticleDOI
Binding of mercury in the rat kidney by metallothionein
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TLDR
Metallothionein is identified as the compound responsible for the selective binding and retention of mercury in the kidney of rats.About:
This article is published in Toxicology and Applied Pharmacology.The article was published on 1970-05-01. It has received 107 citations till now. The article focuses on the topics: Metallothionein & Sephadex.read more
Citations
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Journal ArticleDOI
The interaction of cadium-induced rat renal metallothionein with bivalent mercury in vitro
Daphne Holt,L. Magos,M. Webb +2 more
TL;DR: After treatment with amounts of Hg2+ sufficient to displace completely either the bound Zn2+ and Cd2+, or all of the original cations, the metallothionein has little or no negative charge at pH 8.0 and is not resolved into the two isometallothionins, which characterize the (Cd, Cu, Zn)-thionein, by ion exchange chromatography at this pH.
Book ChapterDOI
Distribution, Tissue Binding and Toxicity of Mercurials
TL;DR: Although there is a continuing problem of occupational exposure to inorganic mercury, possible effects on broader segments of the population due to the widespread dispersal of mercury in the environment has recently become the focus of concern.
Journal ArticleDOI
A naturally occurring cadmium and zinc binding protein from the liver and kidney of Fulmarus glacialis, a pelagic North Atlantic seabird
Journal ArticleDOI
Some effects of selenium status on inorganic mercury metabolism in the rat.
Raymond F. Burk,Raymond F. Burk,Hilliard E. Jordan,Hilliard E. Jordan,Kenneth W. Kiker,Kenneth W. Kiker +5 more
TL;DR: A major effect of selenium status on the metabolism of inorganic mercury seems to be in facilitating the accumulation of mercury by the kidney.
Journal ArticleDOI
Uptake and distribution of mercury in mice from ingesting soluble and insoluble mercury compounds.
TL;DR: The paper presented to compares short term and long term uptake and tissue distribution of mercury in mice from ingesting pure and crude mercuric sulfide to a more soluble Mercuric chloride.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Estimation of the molecular weights of proteins by Sephadex gel-filtration.
TL;DR: The results are similar to those of previous studies, where the objective was to establish a cause-and-effect relationship, rather than a straightforward relationship between the number of cells and the content of the molecule.
Journal ArticleDOI
The gel-filtration behaviour of proteins related to their molecular weights over a wide range
TL;DR: Correlation between elution volume, V(e), and molecular weight was investigated for gel filtration of proteins of molecular weights ranging from 3500 (glucagon) to 820000 (alpha-crystallin) on Sephadex G-200 columns at pH7.5.