Journal ArticleDOI
Binding of mercury in the rat kidney by metallothionein
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TLDR
Metallothionein is identified as the compound responsible for the selective binding and retention of mercury in the kidney of rats.About:
This article is published in Toxicology and Applied Pharmacology.The article was published on 1970-05-01. It has received 107 citations till now. The article focuses on the topics: Metallothionein & Sephadex.read more
Citations
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Acute effects of mercuric chloride on intracellular GSH levels and mercury distribution in the fish Oreochromis aureus.
TL;DR: It would appear that teleostian and mammalian glutathione metabolism may have many similarities, and any changes in organ GSH and mercury levels following just 2 h exposure to mercuric chloride (HgCl/sub 2/).
Journal ArticleDOI
The influence of selenium on binding of inorganic mercury by metallothionein in the kidney and liver of the rat.
Journal ArticleDOI
Protein binding of cadmium, zinc and copper in environmentally insulted limpets Patella vulgata.
A.G. Howard,Graham Nickless +1 more
Journal ArticleDOI
270 MHz proton magnetic resonance spectra of metallothionein.
TL;DR: Proton magnetic resonance measurements employing high resolution PMR spectroscopy at 270 MHz promised to shed more light upon the conformation of metallothionein, the metal binding and the detection of aromatic amino acid residues and revealed that throughout the pD regions from 1.3-6.5 the protein actually remained in the random coil form and no sign of aggregation was detectable.
Book ChapterDOI
Renal metal binding proteins.
TL;DR: The ability of metals, such as cadmium, zinc and mercury, to bind in the liver or kidneys with metallothionein or related proteins is linked with induction of biosynthesis of these proteins.
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
Estimation of the molecular weights of proteins by Sephadex gel-filtration.
TL;DR: The results are similar to those of previous studies, where the objective was to establish a cause-and-effect relationship, rather than a straightforward relationship between the number of cells and the content of the molecule.
Journal ArticleDOI
The gel-filtration behaviour of proteins related to their molecular weights over a wide range
TL;DR: Correlation between elution volume, V(e), and molecular weight was investigated for gel filtration of proteins of molecular weights ranging from 3500 (glucagon) to 820000 (alpha-crystallin) on Sephadex G-200 columns at pH7.5.