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Journal ArticleDOI

Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering

Kurosh Rezwan, +3 more
- 01 Jun 2006 - 
- Vol. 27, Iss: 18, pp 3413-3431
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TLDR
Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
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This article is published in Biomaterials.The article was published on 2006-06-01. It has received 3505 citations till now. The article focuses on the topics: Tissue engineering.

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Citations
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Microstructural and mechanical properties of porous biocomposite scaffolds based on polyvinyl alcohol, nano-hydroxyapatite and cellulose nanocrystals

TL;DR: In this article, the effect of the CNC content on the properties of the biocomposite scaffold was investigated and characterized using field-emission scanning electron microscopy, Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) analysis, porosity and compressive strength measurements, thermal studies, and in-vitro biomineralization and degradation studies.
Journal ArticleDOI

Tungsten Disulfide Nanotubes Reinforced Biodegradable Polymers for Bone Tissue Engineering

TL;DR: Results suggest that chemical composition, the presence of functional groups and individual dispersion of the nanomaterials in the polymer matrix (absence of aggregation of the reinforcing agent) are the key parameters affecting the mechanical properties of nanostructure-reinforced PPF composites.
Journal ArticleDOI

Hydroxyapatite-reinforced polymer biocomposites for synthetic bone substitutes

TL;DR: The effects of the polymer composition and molecular orientation; the HA/polymer interface; and the HA-reinforcement content, morphology, preferred orientation, and size are reviewed with respect to mechanical properties, drawing frequent comparisons between various HA- reinforced polymer composites and bone tissue.
Journal ArticleDOI

Fabrication and in vitro characterization of three-dimensional organic/inorganic scaffolds by robocasting.

TL;DR: In this article, a hybrid organic/inorganic scaffolds with controlled microstructures can be built using robotic assisted deposition at room temperature, and the stiffness of pure polylactide or polycaprolactone scaffolds increased drastically due to polymer densification.
References
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Journal ArticleDOI

Porosity of 3D biomaterial scaffolds and osteogenesis.

TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
Journal ArticleDOI

Scaffolds in tissue engineering bone and cartilage.

TL;DR: Research on the tissue engineering of bone and cartilage from the polymeric scaffold point of view is reviews from a biodegradable and bioresorbable perspective.
Journal ArticleDOI

Bioceramics: From Concept to Clinic

TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article

Bioceramics : from concept to clinic

TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Book

Biomaterials Science: An Introduction to Materials in Medicine

TL;DR: A. Ratner, Biomaterials Science: An Interdisciplinary Endeavor, Materials Science and Engineering--Properties of Materials: J.E. Schoen, and R.J.Ratner, Surface Properties of Materials, and Application of Materials in Medicine and Dentistry.