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Journal ArticleDOI

Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering

Kurosh Rezwan, +3 more
- 01 Jun 2006 - 
- Vol. 27, Iss: 18, pp 3413-3431
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TLDR
Challenges in scaffold fabrication for tissue engineering such as biomolecules incorporation, surface functionalization and 3D scaffold characterization are discussed, giving possible solution strategies.
About
This article is published in Biomaterials.The article was published on 2006-06-01. It has received 3505 citations till now. The article focuses on the topics: Tissue engineering.

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Citations
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Journal ArticleDOI

Bioactive glass scaffolds for bone tissue engineering: state of the art and future perspectives

TL;DR: The review reveals the fact that mechanical strength is not a real limiting factor in the use of bioactive glass scaffolds for bone repair, an observation not often recognized by most researchers and clinicians.
Journal ArticleDOI

Effect of Bioactive Glasses on Angiogenesis: A Review of In Vitro and In Vivo Evidences

TL;DR: The literature discussing in vitro studies which have demonstrated that increases in angiogenic indicators have been achieved through both direct and indirect contact of relevant cells with 45S5 Bioglass((R)) particles or with their dissolution products are reviewed.
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A review of the mechanical behavior of CaP and CaP/polymer composites for applications in bone replacement and repair.

TL;DR: The real limitation for CaPs appears not to be strength necessarily, but toughness and reliability, which are rarely characterized, so research should focus on novel ways of toughening CaPs.
Journal ArticleDOI

Biodegradable Materials for Bone Repair and Tissue Engineering Applications

TL;DR: This review discusses and summarizes the recent developments and advances in the use of biodegradable materials for bone repair purposes, including polymers, ceramics and magnesium alloys, which have attracted much attention for osteologic repair and applications.
Journal ArticleDOI

Fibroblast growth factors: biology, function, and application for tissue regeneration.

TL;DR: The biology and cellular functions of FGFs are introduced and the biomaterials based delivery systems and their current applications for the regeneration of tissues are discussed, including skin, blood vessel, muscle, adipose, tendon/ligament, cartilage, bone, tooth, and nerve tissues.
References
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Journal ArticleDOI

Porosity of 3D biomaterial scaffolds and osteogenesis.

TL;DR: New fabrication techniques, such as solid-free form fabrication, can potentially be used to generate scaffolds with morphological and mechanical properties more selectively designed to meet the specificity of bone-repair needs.
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Scaffolds in tissue engineering bone and cartilage.

TL;DR: Research on the tissue engineering of bone and cartilage from the polymeric scaffold point of view is reviews from a biodegradable and bioresorbable perspective.
Journal ArticleDOI

Bioceramics: From Concept to Clinic

TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Journal Article

Bioceramics : from concept to clinic

TL;DR: The mechanisms of tissue bonding to bioactive ceramics are beginning to be understood, which can result in the molecular design of bioceramics for interfacial bonding with hard and soft tissues.
Book

Biomaterials Science: An Introduction to Materials in Medicine

TL;DR: A. Ratner, Biomaterials Science: An Interdisciplinary Endeavor, Materials Science and Engineering--Properties of Materials: J.E. Schoen, and R.J.Ratner, Surface Properties of Materials, and Application of Materials in Medicine and Dentistry.