Open AccessJournal Article
Biomedical applications of biodegradable polymers
TLDR
Degradable biomaterials have been investigated for biomedical applications with novel materials constantly being developed to meet new challenges as mentioned in this paper, and a review summarizes the most recent advances in the field over the past four years, specifically highlighting new and interesting discoveries in tissue engineering and drug delivery applications.Abstract:
Utilization of polymers as biomaterials has greatly impacted the advancement of modern medicine. Specifically, polymeric biomaterials that are biodegradable provide the significant advantage of being able to be broken down and removed after they have served their function. Applications are wide ranging with degradable polymers being used clinically as surgical sutures and implants. To fit functional demand, materials with desired physical, chemical, biological, biomechanical, and degradation properties must be selected. Fortunately, a wide range of natural and synthetic degradable polymers has been investigated for biomedical applications with novel materials constantly being developed to meet new challenges. This review summarizes the most recent advances in the field over the past 4 years, specifically highlighting new and interesting discoveries in tissue engineering and drug delivery applications.read more
Citations
More filters
Designed biodegradable hydrogel structures prepared by stereolithography using poly(ethylene glycol)/poly(D,L-lactide)-based resins
TL;DR: Porous hydrogel structures with a gyroid pore network architecture showed narrow pore size distributions, excellent pore interconnectivity and good mechanical properties, and the structures showed good cell seeding characteristics, and human mesenchymal stem cells adhered and proliferated well on these materials.
Journal ArticleDOI
Biopolymeric Sustainable Materials and their Emerging Applications
TL;DR: An overview of the latest knowledge of different natural and synthetic-based biodegradable polymers and their fiber-reinforced composites is presented in this paper , which discusses different degradation mechanisms of biopolymer-based composites as well as their sustainability aspects.
Journal ArticleDOI
Recent advancements of nanoparticles application in cancer and neurodegenerative disorders: At a glance.
M. M. Rahman,Md. Rezaul Islam,Shopnil Akash,Mohd Harun-Or-Rashid,Tanmay Ray,Md. Saidur Rahaman,Mahfuzul Islam,Fazilatunnesa Anika,Md. Kawser Hosain,Farjana Islam Aovi,Hassan A. Hemeg,Abdur Rauf,Polrat Wilairatana +12 more
TL;DR: Nanocarriers have been extensively studied and employed for cancerous therapeutic strategies since nanomaterials potentially play a significant role in medical transportation as mentioned in this paper , such as excellent reliability, bioactivity, improved penetration and retention impact, as well as precise targeting and administering.
Journal ArticleDOI
Bone tissue engineering: Anionic polysaccharides as promising scaffolds.
Ponnurengam Malliappan Sivakumar,Abuzer Alp Yetisgin,Sevilay Burcu Sahin,Ebru Demir,Sibel Cetinel +4 more
TL;DR: Bone repair is a self-healing process as mentioned in this paper , and critical-sized bone defects need bone augmentation where bone tissue engineering plays vital role. Bone tissue Engineering (BTE) requires unique combinations of scaffolds, cells, and bio-signal molecules.
Journal ArticleDOI
Recent progress in Mg-based alloys as a novel bioabsorbable biomaterials for orthopedic applications
TL;DR: In this paper , the properties, fabrication, biological functions, and surface modification of Mg-based alloys as novel bioabsorbable biomaterials for orthopedic applications are discussed.
References
More filters
Journal ArticleDOI
Biodegradable polymers as biomaterials
TL;DR: This review summarizes the main advances published over the last 15 years, outlining the synthesis, biodegradability and biomedical applications ofBiodegradable synthetic and natural polymers.
Journal ArticleDOI
Synthetic biodegradable polymers as orthopedic devices.
John Middleton,Arthur J. Tipton +1 more
TL;DR: In this paper, the authors focus on properties of biodegradable polymers which make them ideally suited for orthopedic applications where a permanent implant is not desired, and an overview of biocompatibility and approved devices of particular interest in orthopedics are also covered.
Journal ArticleDOI
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
Journal ArticleDOI
Hyaluronan: its nature, distribution, functions and turnover
TL;DR: Hyaluronan’s nature, distribution, functions and turnover are studied in detail in a large sample of animals from around the world.
Journal ArticleDOI
Bone Tissue Engineering: Recent Advances and Challenges
TL;DR: The fundamentals of bone tissue engineering are discussed, highlighting the current state of this field, and the recent advances of biomaterial and cell-based research, as well as approaches used to enhance bone regeneration.