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Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release

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This article is published in Chemical Reviews.The article was published on 2016-02-08 and is currently open access. It has received 1837 citations till now. The article focuses on the topics: Controlled release.

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Reactive Oxygen Species (ROS)-Based Nanomedicine.

TL;DR: In this article, the intrinsic biochemical properties of reactive oxygen species (ROS) underlie the mechanisms that regulate various physiological functions of living organisms, and they play an essential role in regulating various physiological function.
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Chitosan as a bioactive polymer: Processing, properties and applications.

TL;DR: The most common chitosan processing methods are summarized and some applications of chitOSan in various industrial and biomedical fields are highlighted, including antibacterial activity, non-toxicity, ease of modification, and biodegradability.
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Novel concept of the smart NIR-light-controlled drug release of black phosphorus nanostructure for cancer therapy.

TL;DR: This work proposes a unique concept for precision cancer therapy by external light excitation to release cancer drugs by light activation of black phosphorus (BP) at hydrogel nanostructures for cancer therapy.
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TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy.

TL;DR: The ability of rationally engineered drug–nanoparticle combinations to efficiently modulate tumour-associated macrophages for cancer immunotherapy is demonstrated and R848, an agonist of the toll-like receptors TLR7 and TLR8 identified in a morphometric-based screen, is a potent driver of the M1 phenotype in vitro.
References
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A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

TL;DR: Together, these properties make PEI a promising vector for gene therapy and an outstanding core for the design of more sophisticated devices because its efficiency relies on extensive lysosome buffering that protects DNA from nuclease degradation, and consequent lysOSomal swelling and rupture that provide an escape mechanism for the PEI/DNA particles.
Book

Principles of polymerization

TL;DR: In this paper, the authors present an overview of the properties of polymers and their applications in the literature, including the following: 1.1 Types of Polymers and Polymerization. 2.3 Linear, Branched, and Crosslinked Polymers.
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Stimuli-responsive nanocarriers for drug delivery

TL;DR: Recent advances in the design of nanoscale stimuli-responsive systems that are able to control drug biodistribution in response to specific stimuli, either exogenous (variations in temperature, magnetic field, ultrasound intensity, light or electric pulses) or endogenous (changes in pH, enzyme concentration or redox gradients).
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Diffusion of Univalent Ions Across the Lamellae of Swollen Phospholipids

TL;DR: It is found that as the surface charge of the lipid lamellae is increased, the amount of cation per μmle of lipid increases, and the phospholipid liquid crystalline structures appear to “bind” or “capture” cations.
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Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple.

TL;DR: Estimates can be used to more fully understand the redox biochemistry that results from oxidative stress, which hopefully will provide a rationale and understanding of the cellular mechanisms associated with cell growth and development, signaling, and reductive or oxidative stress.
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