Journal ArticleDOI
Bisphenol AF may cause testosterone reduction by directly affecting testis function in adult male rats.
TLDR
Data demonstrate that BPAF-induced inhibition of testosterone production primarily resulted from the alteration of genes and proteins in the testosterone biosynthesis pathway.About:
This article is published in Toxicology Letters.The article was published on 2012-06-01. It has received 125 citations till now. The article focuses on the topics: Steroid biosynthesis & Luteinizing hormone.read more
Citations
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Scientific Opinion on the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs: Executive summary
TL;DR: The CEF Panel concluded that there is no health concern for any age group from dietary exposure and low health concern from aggregated exposure, although considerable uncertainty in the exposure estimates for non-dietary sources was relatively low.
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Concentrations and profiles of bisphenol A and other bisphenol analogues in foodstuffs from the United States and their implications for human exposure.
TL;DR: Several bisphenol analogues, including BPA, BPF, and BPS, were analyzed in foodstuffs collected from Albany, NY, USA, using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS).
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Bisphenol s, a new bisphenol analogue, in paper products and currency bills and its association with bisphenol a residues.
TL;DR: Among the paper types analyzed, thermal receipt papers were found to be the major sources of human exposure to BPS, and the first report on the occurrence of BPS in paper products and currency bills is reported.
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Acute Toxicity, Teratogenic, and Estrogenic Effects of Bisphenol A and Its Alternative Replacements Bisphenol S, Bisphenol F, and Bisphenol AF in Zebrafish Embryo-Larvae
TL;DR: This first comprehensive analysis on the toxicity and teratogenic effects of the bisphenols BPA, BPS, BPF, and BPAF in zebrafish embryo-larvae and an assessment on their estrogenic mechanisms in an estrogen-responsive transgenic fish Tg(ERE:Gal4ff)(UAS:GFP) show that these BPA alternatives induce similar toxic and estrogenic effects to BPA and that BPAf is more potent than BPA.
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Simultaneous determination of seven bisphenols in environmental water and solid samples by liquid chromatography–electrospray tandem mass spectrometry
TL;DR: This method was successfully applied to real environmental sample analysis, which revealed that all of the tested BPs were present, with the exception of BPB.
References
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Journal ArticleDOI
Analysis of relative gene expression data using real-time quantitative pcr and the 2(-delta delta c(t)) method
TL;DR: The 2-Delta Delta C(T) method as mentioned in this paper was proposed to analyze the relative changes in gene expression from real-time quantitative PCR experiments, and it has been shown to be useful in the analysis of realtime, quantitative PCR data.
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Overview of Steroidogenic Enzymes in the Pathway from Cholesterol to Active Steroid Hormones
Anita H. Payne,Dale B. Hales +1 more
TL;DR: This review presents a detailed description of the enzymes involved in the biosynthesis of active steroid hormones, with emphasis on the human and mouse enzymes and their expression in gonads, adrenal glands, and placenta.
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Molecular Biology of Steroid Hormone Synthesis
TL;DR: Five groups of steroid hormones are generally recognized according to their physiological behavior: mineralocorticoids, which instruct the renal tubules to retain sodium; glucocortics, which are named for their carbohydratemobilizing properties but have many other effects as well; estrogens, which induce female secondary sexual characteristics; progestins, which is essential for reproduction; and androgens, who induce male secondarySexual characteristics.
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In vitro molecular mechanisms of bisphenol A action.
Yelena B. Wetherill,Benson T. Akingbemi,Jun Kanno,John A. McLachlan,Angel Nadal,Carlos Sonnenschein,Cheryl S. Watson,R. Thomas Zoeller,Scott M. Belcher +8 more
TL;DR: This review is a detailed review of published studies that have focused on the mechanistic basis of BPA action in diverse experimental models and an assessment of the strength of the evidence regarding the published BPA research.
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Inhibins, Activins, and Follistatins: Gonadal Proteins Modulating the Secretion of Follicle-Stimulating Hormone
TL;DR: The concept that a gonadal protein, inhibin, specifically regulates FSH secretion was proposed and has now been validated by the isolation and characterization of two forms of inhibin that exert their effects on the pituitary to suppress F SH secretion both in vitro and probably in vivo.