Journal ArticleDOI
Borderline personality disorder: Hypothalamus pituitary adrenal axis and findings from neuroimaging studies
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TLDR
Research on the HPA axis and neuroimaging studies in BPD are reviewed and integrated and it is found that these findings yield important insight into the neurobiology of BPD.About:
This article is published in Psychoneuroendocrinology.The article was published on 2010-01-01. It has received 119 citations till now. The article focuses on the topics: Borderline personality disorder & Major depressive disorder.read more
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Decision making under stress: A selective review
TL;DR: The results from the studies that were included in the review support the assumption that stress affects decision making and emphasize the role of mediating and moderating variables.
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Pituitary-Adrenal and Autonomic Responses to Stress in Women After Sexual and Physical Abuse in Childhood
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The Neurobiology of Mentalizing
Patrick Luyten,Peter Fonagy +1 more
TL;DR: The key assumptions of the mentalizing approach to normal and disrupted development are summarized and the multiple dimensions of mentalizing are discussed and the authors' emerging knowledge of the neural circuits that underlie these dimensions are discussed.
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Reduced plasma oxytocin levels in female patients with borderline personality disorder
TL;DR: The findings indicate dysregulations in the oxytocin system of patients diagnosed with BPD with more longitudinal research being necessary to disentangle the relationship between childhood adversities, oxytoc in system, and psychopathology.
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Genetics of borderline personality disorder: Systematic review and proposal of an integrative model
TL;DR: A systematic review of the literature concerning the genetics of BPD, including familial and twin studies, association studies, and gene-environment interaction studies found no significant associations for the serotonin transporter gene, the tryptophan hydroxylase 1 gene, or the serotonin 1B receptor gene.
References
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Book
Structured clinical interview for DSM-IV axis I disorders : SCID-I : clinical version : scoresheet
TL;DR: The SCID-I is an efficient, user-friendly instrument that covers those DSM-IV diagnoses most commonly seen by clinicians and includes the diagnostic criteria for these disorders with corresponding interview questions and provides extensive documentation of the diagnostic process.
Journal ArticleDOI
The ‘Trier Social Stress Test’ – A Tool for Investigating Psychobiological Stress Responses in a Laboratory Setting
TL;DR: The results suggest that gender, genetics and nicotine consumption can influence the individual's stress responsiveness to psychological stress while personality traits showed no correlation with cortisol responses to TSST stimulation.
Journal ArticleDOI
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
Patrick O. McGowan,Aya Sasaki,Aya Sasaki,Ana C. D'Alessio,Sergiy Dymov,Benoit Labonté,Moshe Szyf,Gustavo Turecki,Michael J. Meaney,Michael J. Meaney +9 more
TL;DR: Findings translate previous results from rat to humans and suggest a common effect of parental care on the epigenetic regulation of hippocampal glucocorticoid receptor expression.
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Maternal Care, Hippocampal Glucocorticoid Receptors, and Hypothalamic-Pituitary-Adrenal Responses to Stress
Dong Liu,Josie Diorio,Josie Diorio,Beth Tannenbaum,Beth Tannenbaum,Christian Caldji,Christian Caldji,Darlene D. Francis,Darlene D. Francis,Alison Freedman,Alison Freedman,Shakti Sharma,Shakti Sharma,Deborah Pearson,Deborah Pearson,Paul M. Plotsky,Paul M. Plotsky,Michael J. Meaney,Michael J. Meaney +18 more
TL;DR: It is suggested that maternal behavior serves to "program" hypothalamic-pituitary-adrenal responses to stress in the offspring.
Journal ArticleDOI
The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies
TL;DR: Preclinical studies suggest that early life stress induces long-lived hyper(re)activity of corticotropin-releasing factor (CRF) systems as well as alterations in other neurotransmitter systems, resulting in increased stress responsiveness.