Journal ArticleDOI
Cadmium induces the expression of specific stress proteins in sea urchin embryos.
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TLDR
Sea urchin embryos represent a simple though significant model system to test how specific stress can simultaneously affect development and protein expression, and the effects of time-dependent continuous exposure to subacute/sublethal cadmium concentrations are studied.About:
This article is published in Biochemical and Biophysical Research Communications.The article was published on 2004-08-13. It has received 105 citations till now. The article focuses on the topics: Paracentrotus lividus.read more
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Cadmium-induced hepatotoxicity in rats and the protective effect of naringenin
J. Renugadevi,S. Milton Prabu +1 more
TL;DR: The present study suggested that naringenin may be beneficial in ameliorating the cadmium-induced oxidative damage in the liver of rats.
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Toxic effects of engineered nanoparticles in the marine environment: model organisms and molecular approaches.
Valeria Matranga,Ilaria Corsi +1 more
TL;DR: Model organisms that have not been conventionally used for risk assessment and the development of eco-toxicogenomic approaches will result in an improved understanding of the mechanistic modes of action of contaminating ENPs in the marine environment.
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UVB radiation prevents skeleton growth and stimulates the expression of stress markers in sea urchin embryos.
TL;DR: The morphological effects observed 1, 24, and 48 h after exposure were correlated with a dose-dependent increase in the level and in the activation of two recognized stress markers consistent with their role in mediating cellular response to stress and suggesting a function in embryo survival.
Book
Marine Invertebrates as Bioindicators of Heavy Metal Pollution
TL;DR: In this paper, a review of recent studies on heavy metal pollution in marine ecosystems and their organisms is presented, including metal speciation, bioaccumulation in biota, as well as abiotic and biotic factors affecting their bioavailability.
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Molecular insight into extreme copper resistance in the extremophilic archaeon 'Ferroplasma acidarmanus' Fer1.
TL;DR: Proteomic analysis of Fer1 cells exposed to Cu(2+) revealed the induction of stress proteins associated with protein folding and DNA repair, suggesting that 'Ferroplasma acidarmanus' Fer1 uses multiple mechanisms for resistance to high levels of copper.
References
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High resolution two-dimensional electrophoresis of proteins.
TL;DR: This technique provides a method for estimation of the number of proteins made by any biological system and can resolve proteins differing in a single charge and consequently can be used in the analysis of in vivo modifications resulting in a change in charge.
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Molecular and cellular mechanisms of cadmium carcinogenesis
TL;DR: It becomes clear that there exist multiple mechanisms which contribute to the carcinogenicity of cadmium, although the relative weights of these contributions are difficult to estimate.
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Oxidative mechanisms in the toxicity of chromium and cadmium ions.
TL;DR: The results clearly indicate that although different mechanisms lead to the production of reactive oxygen species by chromium and cadmium, similar subsequent mechanisms and types of oxidative tissue damage are involved in the overall toxicities.
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Heat Shock Proteins Increase Resistance to Apoptosis
Afshin Samali,Thomas G. Cotter +1 more
TL;DR: Results demonstrate that an increase in cellular levels of hsp 27 or 70, either by a mild heat shock treatment or by stable transfection, increases the resistance of U937 and Wehi-s cells to apoptotic cell death.
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HSP27 and HSP70: potentially oncogenic apoptosis inhibitors.
TL;DR: HSP27 and HSP70 may participate in oncogenesis, as suggested by the fact that overexpression of heat shock proteins can increase the tumorigenic potential of tumor cells.