Journal ArticleDOI
Cerebral blood flow during exercise: mechanisms of regulation
Shigehiko Ogoh,Philip N. Ainslie +1 more
TLDR
This finding indicates that, during heavy exercise, CBF decreases despite the cerebral metabolic demand, and this reduced CBF duringheavy exercise lowers cerebral oxygenation and therefore may act as an independent influence on central fatigue.Abstract:
The response of cerebral vasculature to exercise is different from other peripheral vasculature; it has a small vascular bed and is strongly regulated by cerebral autoregulation and the partial pre...read more
Citations
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Journal ArticleDOI
Utility of transcranial Doppler ultrasound for the integrative assessment of cerebrovascular function.
Christopher K. Willie,Francisco L. Colino,Damian M. Bailey,Yu-Chieh Tzeng,Gordon Binsted,Lee W. Jones,Mark J. Haykowsky,Judith Bellapart,Shigehiko Ogoh,Kurt J. Smith,Jonathan D. Smirl,Trevor A. Day,Samuel J. E. Lucas,Lindsay K. Eller,Philip N. Ainslie +14 more
TL;DR: TCD is an efficient tool to access blood velocities within the cerebral vessels, cerebral autoregulation, cerebrovascular reactivity to CO(2), and neurovascular coupling in both physiological states and in pathological conditions such as stroke and head trauma.
Journal ArticleDOI
Benefits of regular aerobic exercise for executive functioning in healthy populations
Hayley Guiney,Liana Machado +1 more
TL;DR: Examination of exercise-related benefits for specific components of executive functioning in young adults and children indicates that regular engagement in aerobic exercise can provide a simple means for healthy people to optimize a range of executive functions.
Journal ArticleDOI
Effects of incremental exercise on cerebral oxygenation measured by near-infrared spectroscopy: A systematic review
TL;DR: Preliminary results extend the evidence relevant to existing models of central limitations to maximal exercise by indicating that prefrontal oxygenation measured with NIRS in healthy people showed a quadratic response to incremental exercise, rising between moderate and hard intensities, then falling at veryhard intensities.
Journal ArticleDOI
The distribution of blood flow in the carotid and vertebral arteries during dynamic exercise in humans
TL;DR: It is shown that during graded dynamic exercise, the regulation of internal carotid artery blood flow was limited by a large increase in external carotids arterial blood flow, one function of which is thermoregulation during heavy exercise.
OtherDOI
Performance in the Heat—Physiological Factors of Importance for Hyperthermia-Induced Fatigue
TL;DR: An integrative model is proposed that may help understanding the interplay among factors, but also acknowledging that the influence from a given factor depends on the exercise hyperthermia situation.
References
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Journal ArticleDOI
Glucose clamp technique: a method for quantifying insulin secretion and resistance.
TL;DR: Methods for the quantification of beta-cell sensitivity to glucose (hyperglycemic clamp technique) and of tissue sensitivity to insulin (euglycemic insulin clamp technique] are described.
Journal ArticleDOI
Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects.
Peter T. Fox,Marcus E. Raichle +1 more
TL;DR: Dynamic, physiological regulation of CBF by a mechanism (neuronal or biochemical) dependent on neuronal firing per se, but independent of the cerebral metabolic rate of oxygen, is hypothesized.
Journal ArticleDOI
The nitrous oxide method for the quantitative determination of cerebral blood flow in man: theory, procedure and normal values
Seymour S. Kety,Carl F. Schmidt +1 more
TL;DR: The present report constitutes a description of the technique as it has now employed it in over 300 determinations, an examination of its underlying theory and validity, and values obtained with its use in 34 studies on 14 normal young men.
Journal ArticleDOI
Cerebral blood flow and oxygen consumption in man.
TL;DR: In the present study great emphasis will be put on information regarding cerebral oxygen consumption in man, whereas only scant attention will be paid to the intermediary metabolism of the brain.
Journal ArticleDOI
The effects of altered arterial tensions of carbon dioxide and oxygen on cerebral blood flow and cerebral oxygen consumption of normal young men
Seymour S. Kety,Carl F. Schmidt +1 more
TL;DR: Evidence bearing on the intrinsic control of the human cerebral circulation as revealed by quantitative measurements is derived.