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Open AccessJournal ArticleDOI

Chronic post-surgical pain: 10 years on

W.A. Macrae
- 01 Jul 2008 - 
- Vol. 101, Iss: 1, pp 77-86
TLDR
There is a need for education of the medical profession and the general public, so that effective measures are introduced and unnecessary and inappropriate operations minimized, and severe acute postoperative pain emerges as a factor that may be able to influence.
Abstract
In the past ten years there has been recognition that chronic post-surgical pain is a significant problem. This is a complex area of research and although the quality of studies has improved many difficulties remain. Several recent publications have examined risk factors. Severe acute postoperative pain emerges as a factor that we may be able to influence. There is a need for education of the medical profession and the general public, so that effective measures are introduced and unnecessary and inappropriate operations minimized.

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Citations
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Journal ArticleDOI

Incidence of and Risk Factors for Chronic Opioid Use Among Opioid-Naive Patients in the Postoperative Period

TL;DR: Retrospective analysis of administrative health claims to determine the association between chronic opioid use and surgery among privately insured patients between January 1, 2001, and December 31, 2013 found male sex, age older than 50 years, and preoperative history of drug abuse, alcohol abuse, depression, benzodiazepine use, or antidepressant use were associated with chronic opioids use among surgical patients.
Journal ArticleDOI

Poorly controlled postoperative pain: prevalence, consequences, and prevention

TL;DR: Several new opioids have been developed that modulate μ-receptor activity by selectively engaging intracellular pathways associated with analgesia and not those associated with adverse events, creating a wider therapeutic window than unselective conventional opioids.
Journal ArticleDOI

Transition from acute to chronic postsurgical pain: risk factors and protective factors

TL;DR: It is argued that a focus on the transition from acute to chronic pain may reveal important cues that will help to predict who will go on to develop chronic pain and who will not and how to identify the risk factors and protective factors that predict the course of recovery.
References
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Journal ArticleDOI

Neuronal plasticity: increasing the gain in pain.

TL;DR: Here, a conceptual framework for the contribution of plasticity in primary sensory and dorsal horn neurons to the pathogenesis of pain is developed, identifying distinct forms of Plasticity, which are term activation, modulation, and modification, that by increasing gain, elicit pain hypersensitivity.
Journal ArticleDOI

Persistent postsurgical pain: risk factors and prevention

TL;DR: Strategies for identification of patients at risk and for prevention and possible treatment of this important entity of chronic pain are outlined.
Journal ArticleDOI

Health: United States

John A. H. Lee
- 28 Mar 1986 - 
TL;DR: This annual publication for the US Department of Health and Human Services entitled Health: United States is a report to Congress on the health status of the nation and has dropped the essays on selected topics by experts within the government.
Journal ArticleDOI

Multimodal approach to control postoperative pathophysiology and rehabilitation.

TL;DR: While no single technique or drug regimen has been shown to eliminate postoperative morbidity and mortality, multimodal interventions may lead to a major reduction in the undesirable sequelae of surgical injury with improved recovery and reduction in postoperative mortality and overall costs.
Journal ArticleDOI

Chronic pain as an outcome of surgery. A review of predictive factors.

TL;DR: Five groups of surgeries were selected because the incidence of pain is known to be high, thus improving the probability of detecting predictive factors and the natural history of patients with and without persistent pain after surgery provides an opportunity to improve the understanding of the physiology and psychology of chronic pain.
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