Journal ArticleDOI
Cognitive Outcome After Coronary Artery Bypass: A One-Year Prospective Study
Guy M. McKhann,M.A Goldsborough,Louis M. Borowicz,Ola A. Selnes,ScD E.David Mellits,Cheryl Enger,BS Shirley A Quaskey,William A. Baumgartner,Duke E. Cameron,R. Scott Stuart,Timothy J. Gardner +10 more
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TLDR
It is established that the incidence of cognitive decline varies according to the cognitive domain studied and that some patients have persistent and late cognitive changes in specific domains after coronary artery bypass grafting.About:
This article is published in The Annals of Thoracic Surgery.The article was published on 1997-02-01. It has received 183 citations till now. The article focuses on the topics: Cognitive decline & Verbal memory.read more
Citations
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Journal ArticleDOI
Subcortical ischaemic vascular dementia
TL;DR: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy (CADASIL)and some forms of cerebral amyloid angiopathy have a genetic basis.
Journal ArticleDOI
Cognitive Trajectories after Postoperative Delirium
Jane S. Saczynski,Edward R. Marcantonio,Lien Quach,Tamara G. Fong,Alden L. Gross,Sharon K. Inouye,Richard N. Jones +6 more
TL;DR: Delirium is associated with a significant decline in cognitive ability during the first year after cardiac surgery, with a trajectory characterized by an initial decline and prolonged impairment.
Journal ArticleDOI
Cerebral Oxygen Desaturation Predicts Cognitive Decline and Longer Hospital Stay After Cardiac Surgery
James P. Slater,Theresa Guarino,Jessica Stack,Kateki Vinod,Rami Bustami,John Brown,Alejandro L. Rodriguez,Christopher J. Magovern,Thomas S. Zaubler,Kenneth Freundlich,Grant V.S. Parr +10 more
TL;DR: Intraoperative cerebral oxygen desaturation is significantly associated with an increased risk of cognitive decline and prolonged hospital stay after CABG.
Journal ArticleDOI
The assessment of postoperative cognitive function.
TL;DR: A number of recommendations for the design and execution of studies within postoperative cognitive function are presented, and the critical reader may use these recommendations in the evaluation of the literature.
Journal ArticleDOI
Pharmacology and Biological Efficacy of a Recombinant, Humanized, Single-Chain Antibody C5 Complement Inhibitor in Patients Undergoing Coronary Artery Bypass Graft Surgery With Cardiopulmonary Bypass
Jane C. K. Fitch,Scott A. Rollins,Louis A. Matis,Bernadette Alford,Sary F. Aranki,Charles D. Collard,Michael L. Dewar,John A. Elefteriades,Roberta Hines,Gary S. Kopf,Philip Kraker,Lan Li,Ruth O'Hara,Christine S. Rinder,Henry M. Rinder,Richard K. Shaw,Brian G. Smith,Gregory L. Stahl,Stanton K. Shernan +18 more
TL;DR: C5 inhibition significantly attenuates postoperative myocardial injury, cognitive deficits, and blood loss and suggests that C5 inhibition may represent a novel therapeutic strategy for preventing complement-mediated inflammation and tissue injury.
References
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Experimental and clinical neurotoxicology
TL;DR: This book will be indispensable to experimental neuroscientists, toxicologists, and practitioners of human and animal medicine, and provides an authoritative, critical and pithy reference work for public health specialists and those within the legal profession.
Journal ArticleDOI
Neurologic and neuropsychological morbidity following major surgery: comparison of coronary artery bypass and peripheral vascular surgery.
Pamela J. Shaw,David W. Bates,Niall E. F. Cartlidge,Joyce M. French,David Heaviside,Desmond G. Julian,D.A. Shaw +6 more
TL;DR: The difference in frequency and severity of central nervous system complications between the 2 groups is likely to reflect cerebral injury resulting from cardiopulmonary bypass.
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Brain microemboli during cardiac surgery or aortography.
TL;DR: These microvascular events, occurring only in conjunction with major arterial interventions, may be the anatomical correlate of the neurological deficits or moderate to severe intellectual dysfunction seen in at least 24% of patients after cardiac surgical procedures assisted by cardiopulmonary bypass.
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HIV Dementia Scale: a rapid screening test.
TL;DR: The newly developed HIV Dementia Scale (HDS) is a reliable and quantitative scale that is superior to other widely used bedside tests such as the MMSE for identifying HIV dementia.
Journal ArticleDOI
Neuropsychological dysfunction following elective cardiac operation: I. Early assessment
TL;DR: It is suggested that those patients with more precarious heart function, a more protracted operation, and/or increased metabolic disturbances are especially prone to neuropsychological dysfunction following cardiac operations.