Combination of digital mammography with semi-automated 3D breast ultrasound.
Ajay Kapur,Paul L. Carson,Jeffrey Wayne Eberhard,Mitchell M. Goodsitt,Kai Erik Thomenius,Murtuza Lokhandwalla,Donald Joseph Buckley,Marilyn A. Roubidoux,Mark A. Helvie,Rebecca C. Booi,Gerald L. LeCarpentier,Ramon Q. Erkamp,Heang Ping Chan,J. Brian Fowlkes,Jerry A. Thomas,Cynthia Elizabeth Landberg +15 more
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This prototype system takes advantage of many synergies between the co-registered digital mammography and pulse-echo ultrasound image data used for breast cancer detection and diagnosis, and innovative combinations of advanced US and X-ray applications are being implemented and tested along with the basic modes.Abstract:
This paper describes work aimed at combining 3D ultrasound with full-field digital mammography via a semi-automatic prototype ultrasound scanning mechanism attached to the digital mammography system gantry. Initial efforts to obtain high x-ray and ultrasound image quality through a compression paddle are proving successful. Registration between the x-ray mammogram and ultrasound image volumes is quite promising when the breast is stably compressed. This prototype system takes advantage of many synergies between the co-registered digital mammography and pulse-echo ultrasound image data used for breast cancer detection and diagnosis. In addition, innovative combinations of advanced US and X-ray applications are being implemented and tested along with the basic modes. The basic and advanced applications are those that should provide relatively independent information about the breast tissues. Advanced applications include x-ray tomosynthesis, for 3D delineation of mammographic structures, and non-linear elasticity and 3D color flow imaging by ultrasound, for mechanical and physiological information unavailable from conventional, non-contrast x-ray and ultrasound imaging.read more
Citations
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Journal ArticleDOI
A review of breast tomosynthesis. Part II. Image reconstruction, processing and analysis, and advanced applications
TL;DR: A review of breast tomosynthesis research is performed, with an emphasis on its medical physics aspects, including reconstruction, image processing, and analysis, as well as the advanced applications being investigated for breasttomosynthesis.
Journal ArticleDOI
Digital mammography imaging: breast tomosynthesis and advanced applications.
TL;DR: This article discusses recent developments in advanced derivative technologies associated with digital mammography, which hold promise for improving cancer detection and characterization if early results are confirmed by clinical trials.
Journal ArticleDOI
Digital Breast Tomosynthesis: State of the Art.
TL;DR: The observations of increase in cancer detection rates, particularly for invasive cancers, and the reduction in false-positive rates with DBT in prospective trials indicate its benefit for breast cancer screening.
Journal ArticleDOI
Breast cancer imaging: A perspective for the next decade
TL;DR: It appears that the primary imaging tool for breast cancer screening in the next decade will be high-resolution, high-contrast, anatomical x-ray imaging with or without depth information, and there is a trend towards multi-modality systems that combine anatomic with physiologic information.
Journal ArticleDOI
A review of breast ultrasound.
TL;DR: In the future, ultrasound will play a greater role in differentiating benign from malignant masses and in the diagnosis of breast cancer.
References
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Elastic Moduli of Breast and Prostate Tissues under Compression
TL;DR: To evaluate the dynamic range of tissue imaged by elastography, the mechanical behavior of breast and prostate tissue samples subject to compression loading has been investigated and the data show that breast fat tissue has a constant modulus over the strain range tested while the other tissues have a modulus that is dependent on the strain level.
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Comparison of the Performance of Screening Mammography, Physical Examination, and Breast US and Evaluation of Factors that Influence Them: An Analysis of 27,825 Patient Evaluations
TL;DR: Mammographic sensitivity for breast cancer declines significantly with increasing breast density and is independently higher in older women with dense breasts, which significantly increases detection of small cancers and depicts significantly more cancers and at smaller size and lower stage than does PE, which detects independently extremely few cancers.
Book
The visualization toolkit
William J. Schroeder,Ken Martin +1 more
TL;DR: The Visualization Toolkit (VTK) as mentioned in this paper is an open-source, object-oriented software system providing a toolkit of functionality for 3D data visualization, which is used for large-scale data visualization.
Journal ArticleDOI
Digital tomosynthesis in breast imaging.
Loren T. Niklason,B T Christian,L E Niklason,Daniel B. Kopans,D E Castleberry,Beale Opsahl-Ong,C E Landberg,Priscilla J. Slanetz,Angela A. Giardino,Richard D. Moore,D Albagli,M C DeJule,Paul Fitzgerald,D F Fobare,B W Giambattista,R F Kwasnick,J Liu,S J Lubowski,G E Possin,J F Richotte,C Y Wei,R F Wirth +21 more
TL;DR: Tomosynthesis may improve the specificity of mammography with improved lesion margin visibility and may improve early breast cancer detection, especially in women with radiographically dense breasts.
Journal ArticleDOI
A method for measuring the presampled MTF of digital radiographic systems using an edge test device
TL;DR: The edge method provides a convenient measurement of the presampled MTF for digital radiographic systems with good response at low frequencies.