Computer-assisted segmentation of white matter lesions in 3D MR images using support vector machine.
Zhiqiang Lao,Dinggang Shen,Dengfeng Liu,Abbas F. Jawad,Elias R. Melhem,Lenore J. Launer,R. Nick Bryan,Christos Davatzikos +7 more
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TLDR
A computer-assisted WML segmentation method, based on local features extracted from multiparametric magnetic resonance imaging (MRI) sequences, that reduces false positives by using anatomic knowledge and measures of distance from the training set.About:
This article is published in Academic Radiology.The article was published on 2008-03-01 and is currently open access. It has received 235 citations till now. The article focuses on the topics: Population.read more
Citations
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Effects of intensive glucose lowering on brain structure and function in people with type 2 diabetes (ACCORD MIND): A randomised open-label substudy
Lenore J. Launer,Michael E. Miller,Jeff D. Williamson,Ronald M. Lazar,Hertzel C. Gerstein,Anne M. Murray,Mark D. Sullivan,Karen R. Horowitz,Jingzhong Ding,Santica M. Marcovina,Laura C. Lovato,James Lovato,Karen L. Margolis,Patrick J. O'Connor,Edward W. Lipkin,Joy Hirsch,Laura H. Coker,Joseph A. Maldjian,Jeffrey L. Sunshine,Charles Truwit,Christos Davatzikos,R. Nick Bryan +21 more
TL;DR: Although significant differences in TBV favoured the intensive treatment, cognitive outcomes were not different and the findings do not support the use of intensive therapy to reduce the adverse effects of diabetes on the brain in patients with similar characteristics to those of participants.
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A topology-preserving approach to the segmentation of brain images with multiple sclerosis lesions.
TL;DR: Evaluation with both simulated and real data sets demonstrates that the method has an accuracy competitive with state-of-the-art MS lesion segmentation methods, while simultaneously segmenting the whole brain.
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BIANCA (Brain Intensity AbNormality Classification Algorithm): A new tool for automated segmentation of white matter hyperintensities.
Ludovica Griffanti,Giovanna Zamboni,Aamira Khan,Linxin Li,Guendalina Bonifacio,Vaanathi Sundaresan,Ursula G. Schulz,Wilhelm Küker,Marco Battaglini,Peter M. Rothwell,Mark Jenkinson +10 more
TL;DR: The findings suggest that BIANCA, which will be freely available as part of the FSL package, is a reliable method for automated WMH segmentation in large cross-sectional cohort studies.
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White matter hyperintensities and imaging patterns of brain ageing in the general population
Mohamad Habes,Mohamad Habes,Guray Erus,Jon B. Toledo,Tianhao Zhang,Nick Bryan,Lenore J. Launer,Yves Rosseel,Deborah Janowitz,Jimit Doshi,Sandra Van der Auwera,Bettina von Sarnowski,K Hegenscheid,Norbert Hosten,Georg Homuth,Henry Völzke,Ulf Schminke,Wolfgang Hoffmann,Hans J. Grabe,Christos Davatzikos +19 more
TL;DR: The hypothesis that white matter hyperintensities contribute to patterns of brain atrophy found in beyond-normal brain ageing in the general population is supported.
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Segmentation of multiple sclerosis lesions in brain MRI: A review of automated approaches
Xavier Lladó,Arnau Oliver,Mariano Cabezas,Jordi Freixenet,Joan C. Vilanova,Ana Quiles,Laia Valls,Lluís Ramió-Torrentí,ílex Rovira +8 more
TL;DR: The main features of the segmentation algorithms are analysed and the most recent important techniques are classified into different strategies according to their main principle, pointing out their strengths and weaknesses and suggesting new research directions.
References
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