Journal ArticleDOI
Concentrated collagen hydrogels as dermal substitutes.
Christophe Hélary,Isabelle Bataille,Isabelle Bataille,Aicha Abed,Aicha Abed,Corinne Illoul,Annie Anglo,Liliane Louedec,Didier Letourneur,Didier Letourneur,Anne Meddahi-Pellé,Anne Meddahi-Pellé,Marie-Madeleine Giraud-Guille +12 more
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TLDR
The results demonstrate that concentrated collagen hydrogels can be considered as new candidates for dermal substitution because they are is easy to handle, do not contract drastically, favor cell growth, and can be quickly integrated in vivo.About:
This article is published in Biomaterials.The article was published on 2010-01-01. It has received 203 citations till now. The article focuses on the topics: Self-healing hydrogels.read more
Citations
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Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative
TL;DR: Fibroblasts of high population doubling level propagated in vitro, which have left the cell cycle, can carry out the contraction at least as efficiently as cycling cells as discussed by the authors, and the potential uses of the system as an immu- nologically tolerated "tissue" for wound hea ing and as a model for studying fibroblast function are discussed.
Journal ArticleDOI
Biomedical Applications of Biodegradable Polymers
TL;DR: This review summarizes the most recent advances in the field over the past 4 years, specifically highlighting new and interesting discoveries in tissue engineering and drug delivery applications.
Journal ArticleDOI
Current advances and future perspectives in extrusion-based bioprinting.
TL;DR: This paper, presenting a first-time comprehensive review of EBB, discusses the current advancements in EBB technology and highlights future directions to transform the technology to generate viable end products for tissue engineering and regenerative medicine.
Journal ArticleDOI
Direct 3D bioprinting of perfusable vascular constructs using a blend bioink
Weitao Jia,Weitao Jia,Weitao Jia,P. Selcan Gungor-Ozkerim,P. Selcan Gungor-Ozkerim,Yu Shrike Zhang,Yu Shrike Zhang,Yu Shrike Zhang,Kan Yue,Kan Yue,Kai Zhu,Kai Zhu,Kai Zhu,Wanjun Liu,Wanjun Liu,Qingment Pi,Qingment Pi,Batzaya Byambaa,Batzaya Byambaa,Mehmet R. Dokmeci,Mehmet R. Dokmeci,Mehmet R. Dokmeci,Su Ryon Shin,Su Ryon Shin,Su Ryon Shin,Ali Khademhosseini +25 more
TL;DR: A versatile 3D bioprinting strategy that employs biomimetic biomaterials and an advanced extrusion system to deposit perfusable vascular structures with highly ordered arrangements in a single-step process, superior to conventional microfabrication or sacrificial templating approaches for fabrication of the perfusable vasculature.
Journal ArticleDOI
Functional Human Vascular Network Generated in Photocrosslinkable Gelatin Methacrylate Hydrogels.
Ying-Chieh Chen,Ruei-Zeng Lin,Ruei-Zeng Lin,Hao Qi,Hao Qi,Yunzhi Yang,Yunzhi Yang,Hojae Bae,Hojae Bae,Juan M. Melero-Martin,Juan M. Melero-Martin,Ali Khademhosseini,Ali Khademhosseini,Ali Khademhosseini +13 more
TL;DR: The suitability of a photopolymerizable gelatin methacrylate (GelMA) hydrogel to support human progenitor cell‐based formation of vascular networks is demonstrated and it is shown that implantation of cell‐laden GelMA hydrogels into immunodeficient mice results in a rapid formation of functional anastomoses between the bioengineered human vascular network and the mouse vasculature.
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Journal ArticleDOI
Tissue Cells Feel and Respond to the Stiffness of Their Substrate
TL;DR: An understanding of how tissue cells—including fibroblasts, myocytes, neurons, and other cell types—sense matrix stiffness is just emerging with quantitative studies of cells adhering to gels with which elasticity can be tuned to approximate that of tissues.
Journal ArticleDOI
Hydrogels for tissue engineering: scaffold design variables and applications.
Jeanie L. Drury,David J. Mooney +1 more
TL;DR: Hydrogels are an appealing scaffold material because they are structurally similar to the extracellular matrix of many tissues, can often be processed under relatively mild conditions, and may be delivered in a minimally invasive manner.
Journal ArticleDOI
Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells.
James G. Rheinwatd,Howard Green +1 more
TL;DR: Human diploid epidermis epidermal cells have been successfully grown in serial culture and it is possible to isolate keratinocyte clones free of viable fibroblasts, and human diploids keratinocytes appear to have a finite culture lifetime.
Journal ArticleDOI
Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro.
TL;DR: Fibroblasts of high population doubling level propagated in vitro, which have left the cell cycle, can carry out the contraction at least as efficiently as cycling cells.
Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative
TL;DR: Fibroblasts of high population doubling level propagated in vitro, which have left the cell cycle, can carry out the contraction at least as efficiently as cycling cells as discussed by the authors, and the potential uses of the system as an immu- nologically tolerated "tissue" for wound hea ing and as a model for studying fibroblast function are discussed.