Open Access
Conflict of interest statement. None declared.
TLDR
It is found that women over 50 are more likely to have a family history of diabetes, especially if they are obese, than women under the age of 50.Abstract:
Hypertension 66 (20.3%) 24 (24.2%) 30 (16.3%) NS Diabetes 20 (6.2%) 7 (7.1%) 10 (5.4%) NS Excess weight 78 (24%) 27 (27.3%) 44 (23.9%) NS Smokers 64 (19.7%) 17 (17.2%) 35 (19.0%) NS Age >50 years 137 (42.2%) 54 (54.5%) 67 (36.4%) <0.02 Kidney disease 7 (2.2%) 1 (1%) 5 (2.7%) NS Family history, DM 102 (31.4%) 28 (28.3%) 66 (35.9%) NSread more
Citations
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Journal ArticleDOI
The Ribosomal Database Project: improved alignments and new tools for rRNA analysis
James R. Cole,Qiong Wang,Erick Cardenas,Jordan A. Fish,Benli Chai,Ryan J. Farris,A. S. Kulam-Syed-Mohideen,Donna M. McGarrell,Terry L. Marsh,George M. Garrity,James M. Tiedje +10 more
TL;DR: An improved alignment strategy uses the Infernal secondary structure aware aligner to provide a more consistent higher quality alignment and faster processing of user sequences, and a new Pyrosequencing Pipeline that provides tools to support analysis of ultra high-throughput rRNA sequencing data.
Journal ArticleDOI
miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades.
TL;DR: For example, miRDeep2 as mentioned in this paper identifies canonical and non-canonical miRNAs such as those derived from transposable elements and informs on high-confidence candidates that are detected in multiple independent samples.
Journal ArticleDOI
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
Tomas Cermak,Erin L. Doyle,Michelle Christian,Li-Li Wang,Yong Zhang,Clarice Schmidt,Joshua A. Baller,Nikunj V. Somia,Adam J. Bogdanove,Daniel F. Voytas +9 more
TL;DR: A method and reagents for efficiently assembling TALEN constructs with custom repeat arrays are presented and design guidelines based on naturally occurring TAL effectors and their binding sites are described.
Journal ArticleDOI
The Arabidopsis Information Resource (TAIR): improved gene annotation and new tools
Philippe Lamesch,Tanya Z. Berardini,Donghui Li,David Swarbreck,Christopher Wilks,Rajkumar Sasidharan,Robert J. Muller,Kate Dreher,Debbie L. Alexander,Margarita Garcia-Hernandez,Athikkattuvalasu S. Karthikeyan,Cynthia H. Lee,William D. Nelson,Larry Ploetz,Shanker Singh,April Wensel,Eva Huala +16 more
TL;DR: Recent developments include several new genome releases, progress on functional annotation of the genome and the release of several new tools including Textpresso for Arabidopsis which provides the capability to carry out full text searches on a large body of research literature.
Journal ArticleDOI
WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013
TL;DR: By integrating functional categories derived from centrally and publicly curated databases as well as computational analyses, WebGestalt has significantly increased the coverage of functional categories in various biological contexts, leading to a total of 78 612 functional categories.
References
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Journal ArticleDOI
The Ribosomal Database Project: improved alignments and new tools for rRNA analysis
James R. Cole,Qiong Wang,Erick Cardenas,Jordan A. Fish,Benli Chai,Ryan J. Farris,A. S. Kulam-Syed-Mohideen,Donna M. McGarrell,Terry L. Marsh,George M. Garrity,James M. Tiedje +10 more
TL;DR: An improved alignment strategy uses the Infernal secondary structure aware aligner to provide a more consistent higher quality alignment and faster processing of user sequences, and a new Pyrosequencing Pipeline that provides tools to support analysis of ultra high-throughput rRNA sequencing data.
Journal ArticleDOI
miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades.
TL;DR: For example, miRDeep2 as mentioned in this paper identifies canonical and non-canonical miRNAs such as those derived from transposable elements and informs on high-confidence candidates that are detected in multiple independent samples.
Journal ArticleDOI
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
Tomas Cermak,Erin L. Doyle,Michelle Christian,Li-Li Wang,Yong Zhang,Clarice Schmidt,Joshua A. Baller,Nikunj V. Somia,Adam J. Bogdanove,Daniel F. Voytas +9 more
TL;DR: A method and reagents for efficiently assembling TALEN constructs with custom repeat arrays are presented and design guidelines based on naturally occurring TAL effectors and their binding sites are described.
Journal ArticleDOI
The Arabidopsis Information Resource (TAIR): improved gene annotation and new tools
Philippe Lamesch,Tanya Z. Berardini,Donghui Li,David Swarbreck,Christopher Wilks,Rajkumar Sasidharan,Robert J. Muller,Kate Dreher,Debbie L. Alexander,Margarita Garcia-Hernandez,Athikkattuvalasu S. Karthikeyan,Cynthia H. Lee,William D. Nelson,Larry Ploetz,Shanker Singh,April Wensel,Eva Huala +16 more
TL;DR: Recent developments include several new genome releases, progress on functional annotation of the genome and the release of several new tools including Textpresso for Arabidopsis which provides the capability to carry out full text searches on a large body of research literature.
Journal ArticleDOI
WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013
TL;DR: By integrating functional categories derived from centrally and publicly curated databases as well as computational analyses, WebGestalt has significantly increased the coverage of functional categories in various biological contexts, leading to a total of 78 612 functional categories.
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