Journal ArticleDOI
Continuous flow systems. Distribution of residence times
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TLDR
In this article, the authors proposed a method to predict the distribution of residence-times in large systems by using distribution-functions for residencetimes, which can be used to calculate the etficiencies of reactors and blenders.About:
This article is published in Chemical Engineering Science.The article was published on 1995-12-01. It has received 1416 citations till now. The article focuses on the topics: Residence time distribution & Perfect mixing.read more
Citations
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Prospects for Transport Modeling of Process Tanks
TL;DR: In this article, a multidimensional transport model of a process tank is proposed to predict the influence of tank geometry on process performance, which can be used to conclusively determine geometric factors which determine tank performance.
Journal ArticleDOI
Modeling of hydrophobic interaction chromatography for the separation of antibody-drug conjugates and its application towards quality by design
Sebastian Andris,Jürgen Hubbuch +1 more
TL;DR: A mechanistic model for the preparative separation of cysteine-engineered mAbs with different degrees of conjugation with a non-toxic surrogate drug is developed and has great potential to help advance the incorporation of digital tools based on mechanistic models in ADC process development by illustrating their capabilities for efficient process development and increased robustness.
Journal ArticleDOI
Influence of process variables on spray agglomeration process in a continuously operated horizontal fluidized bed
TL;DR: In this paper, a continuous operated spray fluidized bed agglomeration with glass beads and water-based binder hydroxypropylmethylcellulose (HPMC) is presented.
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3D Computational-Fluid-Dynamics Modeling of Horizontal Three-Phase Separators: An Approach for Estimating the Optimal Dimensions
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Modeling and Experimental Studies of Adsorptive Dewatering of Selected Aliphatic Alcohols in Temperature Swing Adsorption System
TL;DR: Based on experimental work, closely coupled with mathematical modeling, an analysis was performed of the adsorptive drying of selected water-aliphatic alcohol solutions in this paper, where the experimental work invol...
References
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Journal ArticleDOI
Mathematics of Adsorption in Beds. VI. The Effect of Longitudinal Diffusion in Ion Exchange and Chromatographic Columns
Leon Lapidus,Neal R. Amundson +1 more
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The Definition and Measurement of Some Characteristics of Mixtures
TL;DR: In this paper, it is shown that the important features of such mixtures can be expressed by two statistically defined quantities, the scale and the intensity of segregation, and methods of measuring these are suggested.