Current trends in
TLDR
The investigation of a case of occupational silicosis in Ohio is described and the impact of hospital-based reporting on surveillance forsilicosis is summarized.Abstract:
Silicosis — Continued Silicosis is a chronic lung disease associated with the inhalation and pulmonary deposition of dust that contains crystalline silica. Through the Sentinel Event Notification System for Occupational Risks (SENSOR)* program, CDC's National Institute for Occupational Safety and Health (NIOSH) is assessing practical models for implementing state-based surveillance of silicosis and linking follow-up intervention activities to surveillance reports. From 1989 through 1992, the Ohio Department of Health (ODH) SENSOR program identified silicosis cases through reports of Bureau of Workers' Compensation (BWC) claims, physician reports, and death certificates. The addition in 1993 of hospital discharge reports as an ascertainment source resulted in a substantial increase in the number of silicosis case reports identified annually (Table 1). This report describes the investigation of a case of occupational silicosis in Ohio and summarizes the impact of hospital-based reporting on surveillance for silicosis in Case Report In September 1991, a case report † was sent to ODH by an infectious disease specialist who was treating a 55-year-old sandblaster with advanced silicosis and an associated Mycobacterium kansasii infection § (2). In January 1992, NIOSH and ODH conducted a joint investigation at the worker's place of employment—a metal preparation shop—to evaluate current levels of exposure to respirable crystalline silica and to screen co-workers for silicosis. The investigation detected excessive exposures to respirable crystalline silica (2–5). Chest radiology revealed radiographic abnormalities consistent with pneumoconiosis in four of 16 current and former workers *SENSOR is a program of cooperative agreements with state health departments to develop surveillance and intervention strategies for selected occupational conditions. The National Institute for Occupational Safety and Health currently supports SENSOR silicosis programs in seven states and Wisconsin). † Case reports should be submitted for persons with a physician's provisional diagnosis of silicosis, a chest radiograph interpreted as consistent with silicosis, or pathologic findings consistent with silicosis (1).read more
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Genetic engineering of rice for resistance to sheath blight and other agronomic characters
S.K. Datta,C. Quimio,Lina Torrizo,K. Datta,M. F. Alam,E. Abrigo,N. Oliva,M. S. Alejar,S. Biswas,S. Mukthukrishnan,Ingo Potrykus,T. Setter,T. W. Mew,G.S. Khush +13 more
TL;DR: The degree of resistance displayed by the transgenic plants to this pathogen correlated with the level of chitinase expression, which indicated resistance to the sheath blight pathogen Rhizoctonia solani.
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The cell biology of rabies virus: using stealth to reach the brain.
TL;DR: This Review summarizes the current knowledge of the replication cycle of rabies virus and virus– host cell interactions, both of which are fundamental elements in the quest to understand the life cycle of rabid virus and the pathogenesis of Rabies.
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Exploring chemical space for drug discovery using the chemical universe database.
TL;DR: Open access sources of molecules, the classification and representation of chemical space using molecular quantum numbers (MQN), its exhaustive enumeration in form of the chemical universe generated databases (GDB), and examples of using these databases for prospective drug discovery are discussed.
Mechanisms of oxidant stress-induced acute tissue injury. controversies, contradictions, and paradoxes
TL;DR: A large body of experimental evidence has accumulated from pharmacological intervention studies that suggests an important role for reactive oxygen species in numerous pathophysiological processes, such as recruitment of inflammatory cells by upregulation of adhesion molecules and generation of chemotactic factors, and are necessary for protease-mediated cell injury as discussed by the authors.
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Soybean (Glycine max) Leaf Extract Based Green Synthesis of Palladium Nanoparticles
Ramesh Kumar Petla,Singaravelu Vivekanandhan,Manjusri Misra,Amar K. Mohanty,N. Satyanarayana +4 more
TL;DR: The phase purity of the synthesized palladium nanoparticles was investigated through X-Ray Diffraction (XRD) analysis and the obtained pattern was compared with JCPDS data as mentioned in this paper.
References
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Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products.
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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
TL;DR: This assay is very reproducible and rapid with the dye binding process virtually complete in approximately 2 min with good color stability for 1 hr with little or no interference from cations such as sodium or potassium nor from carbohydrates such as sucrose.
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Molecular Cloning: A Laboratory Manual
TL;DR: Molecular Cloning has served as the foundation of technical expertise in labs worldwide for 30 years as mentioned in this paper and has been so popular, or so influential, that no other manual has been more widely used and influential.
Journal Article
Cleavage of structural proteins during the assemble of the head of bacterio-phage T4
TL;DR: Using an improved method of gel electrophoresis, many hitherto unknown proteins have been found in bacteriophage T4 and some of these have been identified with specific gene products as mentioned in this paper.