Journal ArticleDOI
Development of the asthma control test: A survey for assessing asthma control
Robert A. Nathan,Christine A. Sorkness,Mark Kosinski,Michael Schatz,James T.C. Li,Philip Marcus,John J. Murray,T.B. Pendergraft +7 more
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TLDR
Results reinforce the usefulness of a brief, easy to administer, patient-based index of asthma control.Abstract:
Background Asthma guidelines indicate that the goal of treatment should be optimum asthma control In a busy clinic practice with limited time and resources, there is need for a simple method for assessing asthma control with or without lung function testing Objectives The objective of this article was to describe the development of the Asthma Control Test (ACT), a patient-based tool for identifying patients with poorly controlled asthma Methods A 22-item survey was administered to 471 patients with asthma in the offices of asthma specialists The specialist's rating of asthma control after spirometry was also collected Stepwise regression methods were used to select a subset of items that showed the greatest discriminant validity in relation to the specialist's rating of asthma control Internal consistency reliability was computed, and discriminant validity tests were conducted for ACT scale scores The performance of ACT was investigated by using logistic regression methods and receiver operating characteristic analyses Results Five items were selected from regression analyses The internal consistency reliability of the 5-item ACT scale was 084 ACT scale scores discriminated between groups of patients differing in the specialist's rating of asthma control (F = 345, P P 1 (F = 43, P = 0052) As a screening tool, the overall agreement between ACT and the specialist's rating ranged from 71% to 78% depending on the cut points used, and the area under the receiver operating characteristic curve was 077 Conclusion Results reinforce the usefulness of a brief, easy to administer, patient-based index of asthma controlread more
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Getting Control of Uncontrolled Asthma
TL;DR: Current global guidelines for the assessment and management of asthma control are discussed and the broad spectrum of novel therapeutic agents currently under development for the treatment of asthma is summarized, including anticholinergics, chemoattractant receptor-homologous molecules expressed on T-helper 2 lymphocyte antagonists, and anti-interleukin (IL)-5, anti-IL-13, and self-management agents.
Journal ArticleDOI
Impact of an Adherence Intervention Program on Medication Adherence Barriers, Asthma Control, and Productivity/Daily Activities in Patients With Asthma
Jinhee Park,James Jackson,Elizabeth P. Skinner,Karlene Ranghell,Jane Saiers,Becky J. Cherney +5 more
TL;DR: Programs incorporating a clinical assessment tool such as the ASK-20 for identifying a broad range of risk factors for nonadherence and for developing patient-specific intervention may reduce adherence barriers and improved disease control and ability to perform daily activities in patients with asthma.
Journal ArticleDOI
Examining the role of patients’ experiences as a resource for choice and decision-making in health care: a creative, interdisciplinary mixed-method study in digital health
Sue Ziebland,John Powell,Pamela Briggs,Crispin Jenkinson,Sally Wyke,Elizabeth Sillence,Peter R. Harris,Rafael Perera,Fadhila Mazanderani,Angela Martin,Louise Locock,Laura Kelly,Margaret Booth,Bob Gann,Nicola Newhouse,Andrew Farmer +15 more
TL;DR: Whether, when and how the NHS should incorporate PEx into online health information and elucidate the mechanisms through which PEx might influence health are investigated, a tool to measure the effects of online PEx is developed and how this can be measured is explored.
Journal ArticleDOI
Impact of exhaled nitric oxide measurements on treatment decisions in an asthma specialty clinic
TL;DR: Measurement of FeNO augments routine clinical assessment of asthma by measuring airway inflammation and has important long-term asthma management implications, most notably the potential to lower the costs and morbidity associated with asthma exacerbation.
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Leukotriene-Receptor Antagonists Versus Placebo in the Treatment of Asthma in Adults and Adolescents
Michael Miligkos,Raveendhara R. Bannuru,Hadeel Alkofide,Sucharita R. Kher,Christopher H. Schmid,Ethan M Balk +5 more
TL;DR: In this article, a systematic review of 50 patients with mild asthma who were treated with leukotriene-receptor antagonists (LTRAs) compared with placebo is presented.
References
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The meaning and use of the area under a receiver operating characteristic (ROC) curve.
TL;DR: A representation and interpretation of the area under a receiver operating characteristic (ROC) curve obtained by the "rating" method, or by mathematical predictions based on patient characteristics, is presented and it is shown that in such a setting the area represents the probability that a randomly chosen diseased subject is (correctly) rated or ranked with greater suspicion than a random chosen non-diseased subject.
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TL;DR: This paper refines the statistical comparison of the areas under two ROC curves derived from the same set of patients by taking into account the correlation between the areas that is induced by the paired nature of the data.
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Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes
Ira B. Wilson,Paul D. Cleary +1 more
TL;DR: This model proposes a taxonomy or classification scheme for different measures of health outcome, dividing these outcomes into five levels: biological and physiological factors, symptoms, functioning, general health perceptions, and overall quality of life.
Journal ArticleDOI
Development and validation of a questionnaire to measure asthma control
TL;DR: The Asthma Control Questionnaire has strong evaluative and discriminative properties and can be used with confidence to measure asthma control.
Journal Article
Surveillance for asthma--United States, 1980-1999.
David M. Mannino,David M. Homa,Lara J. Akinbami,Jeanne E. Moorman,Charon Gwynn,Stephen C. Redd +5 more
TL;DR: In this paper, the authors present national data regarding self-reported asthma prevalence, school and work days lost because of asthma, and asthma-associated activity limitations (1980-1996); asthmaassociated outpatient visits, asthmaassociated hospitalizations, asthma associated hospitalizations and asthmaassociated deaths.
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