Journal ArticleDOI
Development of the asthma control test: A survey for assessing asthma control
Robert A. Nathan,Christine A. Sorkness,Mark Kosinski,Michael Schatz,James T.C. Li,Philip Marcus,John J. Murray,T.B. Pendergraft +7 more
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TLDR
Results reinforce the usefulness of a brief, easy to administer, patient-based index of asthma control.Abstract:
Background Asthma guidelines indicate that the goal of treatment should be optimum asthma control In a busy clinic practice with limited time and resources, there is need for a simple method for assessing asthma control with or without lung function testing Objectives The objective of this article was to describe the development of the Asthma Control Test (ACT), a patient-based tool for identifying patients with poorly controlled asthma Methods A 22-item survey was administered to 471 patients with asthma in the offices of asthma specialists The specialist's rating of asthma control after spirometry was also collected Stepwise regression methods were used to select a subset of items that showed the greatest discriminant validity in relation to the specialist's rating of asthma control Internal consistency reliability was computed, and discriminant validity tests were conducted for ACT scale scores The performance of ACT was investigated by using logistic regression methods and receiver operating characteristic analyses Results Five items were selected from regression analyses The internal consistency reliability of the 5-item ACT scale was 084 ACT scale scores discriminated between groups of patients differing in the specialist's rating of asthma control (F = 345, P P 1 (F = 43, P = 0052) As a screening tool, the overall agreement between ACT and the specialist's rating ranged from 71% to 78% depending on the cut points used, and the area under the receiver operating characteristic curve was 077 Conclusion Results reinforce the usefulness of a brief, easy to administer, patient-based index of asthma controlread more
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Assessment of Immune-Related Interstitial Lung Disease in Patients With NSCLC Treated with Immune Checkpoint Inhibitors: A Multicenter Prospective Study.
Yuzo Suzuki,Masato Karayama,Tomohiro Uto,Masato Fujii,Takashi Matsui,Kazuhiro Asada,Hideki Kusagaya,Masato Kato,Hiroyuki Matsuda,Shun Matsuura,Mikio Toyoshima,Kazutaka Mori,Yasuhiro Ito,Takafumi Koyauchi,Hideki Yasui,Hironao Hozumi,Kazuki Furuhashi,Noriyuki Enomoto,Tomoyuki Fujisawa,Yutaro Nakamura,Naoki Inui,Takafumi Suda +21 more
TL;DR: Assessment of spirometry and daily dyspnea before ICI treatment may be useful to monitor and manage NSCLC patients and combination assessment of %FVC and %FEV1 successfully classified patients at risk for ir-ILD development.
Journal ArticleDOI
Discrepancies between lung function and asthma control: Asthma perception and association with demographics and anxiety
TL;DR: The findings encourage further research using the reported method of classifying asthma patients into perceiver categories and indicate that a majority of underperceivers were characterized by being African American and having low asthma-specific anxiety.
Journal ArticleDOI
Sex-Specific Asthma Phenotypes, Inflammatory Patterns, and Asthma Control in a Cluster Analysis.
TL;DR: This study identified heterogeneous characteristics between sexes of asthma phenotypes in females and males, and showed atopy with eosinophil-predominant and obese with neutrophil- Predominant inflammation.
Journal ArticleDOI
The contribution of sublingual immunotherapy to the achievement of control in birch-related mild persistent asthma: A real-life randomised trial
Maurizio Marogna,C. Braidi,M.E. Bruno,C. Colombo,F Colombo,Alessandro Massolo,L. Palumbo,Enrico Compalati +7 more
TL;DR: For patients with respiratory allergy due to birch pollen and mild persistent asthma, sublingual immunotherapy added to low-dose inhaled corticosteroids appears effective in maintaining long-term seasonal asthma control, representing a safe opportunity to reduce the cumulative amount of delivered corticosterone.
Journal ArticleDOI
Evaluation of allergic rhinitis and asthma control in a Portuguese community pharmacy setting.
TL;DR: Using a simple self-assessment questionnaire, such as the CARAT, pharmacists can help identify patients with uncontrolled ARA disease, which is an important first step to change patients' knowledge about their disease, with an ultimate goal of improving ARA outcomes.
References
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Journal ArticleDOI
The meaning and use of the area under a receiver operating characteristic (ROC) curve.
TL;DR: A representation and interpretation of the area under a receiver operating characteristic (ROC) curve obtained by the "rating" method, or by mathematical predictions based on patient characteristics, is presented and it is shown that in such a setting the area represents the probability that a randomly chosen diseased subject is (correctly) rated or ranked with greater suspicion than a random chosen non-diseased subject.
Journal ArticleDOI
A method of comparing the areas under receiver operating characteristic curves derived from the same cases.
TL;DR: This paper refines the statistical comparison of the areas under two ROC curves derived from the same set of patients by taking into account the correlation between the areas that is induced by the paired nature of the data.
Journal ArticleDOI
Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes
Ira B. Wilson,Paul D. Cleary +1 more
TL;DR: This model proposes a taxonomy or classification scheme for different measures of health outcome, dividing these outcomes into five levels: biological and physiological factors, symptoms, functioning, general health perceptions, and overall quality of life.
Journal ArticleDOI
Development and validation of a questionnaire to measure asthma control
TL;DR: The Asthma Control Questionnaire has strong evaluative and discriminative properties and can be used with confidence to measure asthma control.
Journal Article
Surveillance for asthma--United States, 1980-1999.
David M. Mannino,David M. Homa,Lara J. Akinbami,Jeanne E. Moorman,Charon Gwynn,Stephen C. Redd +5 more
TL;DR: In this paper, the authors present national data regarding self-reported asthma prevalence, school and work days lost because of asthma, and asthma-associated activity limitations (1980-1996); asthmaassociated outpatient visits, asthmaassociated hospitalizations, asthma associated hospitalizations and asthmaassociated deaths.
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