Journal ArticleDOI
Development of the asthma control test: A survey for assessing asthma control
Robert A. Nathan,Christine A. Sorkness,Mark Kosinski,Michael Schatz,James T.C. Li,Philip Marcus,John J. Murray,T.B. Pendergraft +7 more
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TLDR
Results reinforce the usefulness of a brief, easy to administer, patient-based index of asthma control.Abstract:
Background Asthma guidelines indicate that the goal of treatment should be optimum asthma control In a busy clinic practice with limited time and resources, there is need for a simple method for assessing asthma control with or without lung function testing Objectives The objective of this article was to describe the development of the Asthma Control Test (ACT), a patient-based tool for identifying patients with poorly controlled asthma Methods A 22-item survey was administered to 471 patients with asthma in the offices of asthma specialists The specialist's rating of asthma control after spirometry was also collected Stepwise regression methods were used to select a subset of items that showed the greatest discriminant validity in relation to the specialist's rating of asthma control Internal consistency reliability was computed, and discriminant validity tests were conducted for ACT scale scores The performance of ACT was investigated by using logistic regression methods and receiver operating characteristic analyses Results Five items were selected from regression analyses The internal consistency reliability of the 5-item ACT scale was 084 ACT scale scores discriminated between groups of patients differing in the specialist's rating of asthma control (F = 345, P P 1 (F = 43, P = 0052) As a screening tool, the overall agreement between ACT and the specialist's rating ranged from 71% to 78% depending on the cut points used, and the area under the receiver operating characteristic curve was 077 Conclusion Results reinforce the usefulness of a brief, easy to administer, patient-based index of asthma controlread more
Citations
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Assessing Asthma control in UK primary care: Use of routinely collected prospective observational consultation data to determine appropriateness of a variety of control assessment models
TL;DR: In the absence of a gold standard for assessing asthma control in primary care, the results indicate that the RCP-3Qs is an effective control assessment tool but, for maximum effect, the expanded scoring model should be used.
Journal ArticleDOI
Relationship Between Comorbidity and Asthma Control
Luis Pérez de Llano,Francisco Carballada González,Olalla Castro Añón,Marlies Pizarro Perea,Manuel Vázquez Caruncho,Adolfo Baloira Villar +5 more
TL;DR: Assessment of the correlation between the asthma control test (ACT) and the fraction of exhaled nitric oxide (FENO) found that aggravating comorbidities are more common in patients with sub-optimal control.
Journal ArticleDOI
Lansoprazole Is Associated with Worsening Asthma Control in Children with the CYP2C19 Poor Metabolizer Phenotype.
Jason E. Lang,Janet T. Holbrook,Edward B. Mougey,Christine Y. Wei,Robert A. Wise,W. Gerald Teague,John J. Lima +6 more
TL;DR: Children with the PM phenotype developed worse asthma control after 6 months of lansoprazole treatment for poorly controlled asthma, and increased exposure to proton pump inhibitor may worsen asthma control by altering responses to respiratory infections.
Mayo Clinic: Multidisciplinary Teamwork, Physician-Led Governance, and Patient-Centered Culture Drive World-Class Health Care
TL;DR: The Mayo Clinic is the world's oldest and largest integrated multispe cialty group medical practice, combining clinical practice, education, and research at the regional, national, and international levels for the benefit of individuals with routine as well as complex health care needs.
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Asthma and Respiratory Foundation NZ adult asthma guidelines: a quick reference guide.
Richard Beasley,Robert J. Hancox,Matire Harwood,Kyle Perrin,Betty Poot,Janine Pilcher,Jim Reid,Api Talemaitoga,Darmiga Thayabaran +8 more
TL;DR: The purpose of the Asthma and Respiratory Foundation NZ Adult Asthma Guidelines is to provide simple, practical and evidence-based recommendations for the diagnosis, assessment and management of asthma in adults (aged 16 and over) in a quick reference format.
References
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The meaning and use of the area under a receiver operating characteristic (ROC) curve.
TL;DR: A representation and interpretation of the area under a receiver operating characteristic (ROC) curve obtained by the "rating" method, or by mathematical predictions based on patient characteristics, is presented and it is shown that in such a setting the area represents the probability that a randomly chosen diseased subject is (correctly) rated or ranked with greater suspicion than a random chosen non-diseased subject.
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A method of comparing the areas under receiver operating characteristic curves derived from the same cases.
TL;DR: This paper refines the statistical comparison of the areas under two ROC curves derived from the same set of patients by taking into account the correlation between the areas that is induced by the paired nature of the data.
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Linking clinical variables with health-related quality of life. A conceptual model of patient outcomes
Ira B. Wilson,Paul D. Cleary +1 more
TL;DR: This model proposes a taxonomy or classification scheme for different measures of health outcome, dividing these outcomes into five levels: biological and physiological factors, symptoms, functioning, general health perceptions, and overall quality of life.
Journal ArticleDOI
Development and validation of a questionnaire to measure asthma control
TL;DR: The Asthma Control Questionnaire has strong evaluative and discriminative properties and can be used with confidence to measure asthma control.
Journal Article
Surveillance for asthma--United States, 1980-1999.
David M. Mannino,David M. Homa,Lara J. Akinbami,Jeanne E. Moorman,Charon Gwynn,Stephen C. Redd +5 more
TL;DR: In this paper, the authors present national data regarding self-reported asthma prevalence, school and work days lost because of asthma, and asthma-associated activity limitations (1980-1996); asthmaassociated outpatient visits, asthmaassociated hospitalizations, asthma associated hospitalizations and asthmaassociated deaths.
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