Journal ArticleDOI
Developmental patterning and segregation of alkaloids in areca nut (seed of Areca catechu) revealed by magnetic resonance and mass spectrometry imaging.
Amitava Srimany,Christy George,Hemanta R. Naik,Danica Glenda Pinto,Narayanan Chandrakumar,Thalappil Pradeep +5 more
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TLDR
It is revealed that white and brown regions start forming within the nut when the liquid within starts solidifying, and the transport of molecules with maturity and corresponding pattern formation are expected to be associated with a multitude of physiochemical changes.About:
This article is published in Phytochemistry.The article was published on 2016-05-01. It has received 41 citations till now. The article focuses on the topics: Arecoline & Arecaidine.read more
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Mass Spectrometry Imaging: A Review of Emerging Advancements and Future Insights.
TL;DR: The combination of information gained from mass spectrometry (MS) and visualization of spatial distributions in thin sample sections makes this a valuable chemical analysis tool useful for biological specimen characterization.
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Review and perspectives on the applications of mass spectrometry imaging under ambient conditions.
Consuelo J. Perez,Aafreen K. Bagga,Shamina Saiyara Prova,Maryam Yousefi Taemeh,Demian R. Ifa +4 more
TL;DR: This review summarizes recent advances in the field with respect to the implementation of new ambient ionization techniques and current applications in the last 5 years and focuses on imaging applications in topics related to animal whole bodies and tissues, single cells, cancer diagnostics and biomarkers, microbial cultures and co-cultures, plant and natural product metabolomics, and forensic applications.
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Bioactive compounds and health benefits of some palm species traditionally used in Africa and the Americas - A review
TL;DR: The phytochemical composition and the pharmacological properties of these important ethno-medicinal palms are discussed, aiming to provide a contribution to future research prospects and represent a significant advance for the implementation of new opportunities for human health.
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Multimodal Imaging Mass Spectrometry: Next Generation Molecular Mapping in Biology and Medicine.
TL;DR: This review describes MALDI, SIMS, and DESI imaging mass spectrometric technologies and how these have been integrated with other analytical modalities such as microscopy, transcriptomics, spectroscopy, and electrochemistry in a field termed multimodal imaging.
Journal ArticleDOI
Intoxication and substance use disorder to Areca catechu nut containing betel quid: A review of epidemiological evidence, pharmacological basis and social factors influencing quitting strategies.
Peter. G. Osborne,Peter. G. Osborne,Ying-Chin Ko,Ming-Tsang Wu,Chien-Hung Lee,Chien-Hung Lee +5 more
TL;DR: The limited understanding of pharmacological basis of intoxication and SUD determines there are no pharmacological replacement therapies for ANcBQ SUD.
References
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Mass Spectrometry Sampling Under Ambient Conditions with Desorption Electrospray Ionization
TL;DR: The DESI phenomenon was observed both in the case of conductive and insulator surfaces and for compounds ranging from nonpolar small molecules such as lycopene, the alkaloid coniceine, and small drugs, through polar compounds such as peptides and proteins.
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Dietary Polyphenols and Their Biological Significance
TL;DR: The biological mechanisms of action and protective effects of dietary polyphenols are described, and the most recent literature on the subject is covered.
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Alert for an epidemic of oral cancer due to use of the betel quid substitutes gutkha and pan masala: a review of agents and causative mechanisms
TL;DR: Evidence that strongly supports causative mechanisms for genotoxicity and carcinogenicity of these substitute products, including gutkha and pan masala, are strongly implicated in the recent increase in the incidence of oral submucous fibrosis is reviewed.
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Mass Spectrometry: Recent Advances in Direct Open Air Surface Sampling/Ionization
TL;DR: This review focuses on laser-Based Hybrid Techniques Coupled to ESI or Plasma Ionization, as well as two-Step Thermal/Mechanical Desorption/ Ablation (Non-Laser) Techniques, which were developed in this review.
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Role of areca nut in betel quid-associated chemical carcinogenesis: current awareness and future perspectives
TL;DR: It would appear that AN toxicity is not completely due to its polyphenol, tannin and alkaloid content, and further studies are needed to delineate the metabolism of AN ingredient and their roles in the multi-step chemical carcinogenesis, to enhance the success of the future chemoprevention of oral cancer and oral submucous fibrosis.