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Open AccessJournal ArticleDOI

Diagnosis and Classification of Diabetes Mellitus

Vittorio Basevi
- 06 Feb 2011 - 
TLDR
The chronic hyperglycemia of diabetes is associated with long-term damage, dys-function, and failure of differentorgans, especially the eyes, kidneys, nerves, heart, and blood vessels.
About
This article is published in Diabetes Care.The article was published on 2011-02-06 and is currently open access. It has received 13077 citations till now. The article focuses on the topics: Prediabetes & Impaired fasting glucose.

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Citations
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The Definition of Insulin Resistance Using HOMA-IR for Americans of Mexican Descent Using Machine Learning

TL;DR: The study showed that the best cutoff of HOMA-IR for identifying those with insulin resistance is 3.80, a critical fundamental for the further efforts to improve the public health of this Hispanic population.
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High-Dose Vitamin D Supplementation in People With Prediabetes and Hypovitaminosis D

TL;DR: In individuals with prediabetes and hypovitaminosis D, doses of vitamin D supplementation designed to raise serum 25-OHD levels into the upper-normal range for 1 year had no effect on insulin secretion, insulin sensitivity, or the development of diabetes compared with placebo administration.
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Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic β-cell dysfunction in streptozotocin- nicotinamide-induced diabetic rats.

TL;DR: It is first‐time reported that the oral administration of resveratrol may effectively rescue β‐cells from oxidative damage without affecting their function and structural integrity and exhibits significant antidiabetic potential.
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Biomarkers in diabetes: hemoglobin A1c, vascular and tissue markers.

TL;DR: In the future, the authors can be optimistic that new blood and tissue-based biomarkers will enable the detection, prevention, and treatment of diabetes and its complications long before overt disease develops.
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The STRIDE weight loss and lifestyle intervention for individuals taking antipsychotic medications: a randomized trial.

TL;DR: Individuals taking antipsychotic medications can lose weight and improve fasting glucose levels, and increasing reach of the intervention is an important future step.
References
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Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.

TL;DR: In this paper, the authors compared a lifestyle intervention with metformin to prevent or delay the development of Type 2 diabetes in nondiabetic individuals. And they found that the lifestyle intervention was significantly more effective than the medication.
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International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy.

TL;DR: The Brazilian study provided evidence that adverse perinatal outcomes are associated with levels of maternal glycemia below those diagnostic of GDM by American Diabetes Association or World Health Organization criteria, however, the results were potentially confounded by the treatment of G DM.
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Follow-up report on the diagnosis of diabetes mellitus.

TL;DR: The International Expert Committee was convened to reexamine the classification and diagnostic criteria of diabetes, which were based on the 1979 publication of the National Diabetes Data Group and subsequent WHO study group and adopted several changes to the diagnostic criteria for diabetes and for lesser degrees of impaired glucose regulation (IFG/IGT).
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Effect of treatment of gestational diabetes mellitus on pregnancy outcomes

TL;DR: Treatment of gestational diabetes reduces serious perinatal morbidity and may also improve the woman's health-related quality of life.
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