Diagnosis and Classification of Diabetes Mellitus
TLDR
The chronic hyperglycemia of diabetes is associated with long-term damage, dys-function, and failure of differentorgans, especially the eyes, kidneys, nerves, heart, and blood vessels.About:
This article is published in Diabetes Care.The article was published on 2011-02-06 and is currently open access. It has received 13077 citations till now. The article focuses on the topics: Prediabetes & Impaired fasting glucose.read more
Citations
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Metabolite Profiles During Oral Glucose Challenge
Jennifer E. Ho,Martin G. Larson,Martin G. Larson,Ramachandran S. Vasan,Ramachandran S. Vasan,Anahita Ghorbani,Susan Cheng,Susan Cheng,Eugene P. Rhee,Eugene P. Rhee,Jose C. Florez,Jose C. Florez,Clary B. Clish,Robert E. Gerszten,Robert E. Gerszten,Thomas J. Wang,Thomas J. Wang +16 more
TL;DR: It is suggested that unique metabolic phenotypes can be unmasked by OGTT in the prediabetic state and changes in 91 metabolites representing distinct biological pathways that are perturbed in response to an OGTT are demonstrated.
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Antidiabetic and antihyperlipidemic activity of Piper longum root aqueous extract in STZ induced diabetic rats.
Shaik Abdul Nabi,Ramesh B. Kasetti,Swapna Sirasanagandla,Thandaiah Krishna Tilak,Malaka Venkateshwarulu Jyothi Kumar,Chippada Appa Rao +5 more
TL;DR: It is concluded that the plant extract is capable of managing hyperglycemia and complications of diabetes in STZ induced diabetic rats and may be considered as one of the potential sources for the isolation of new oral anti hypoglycemic agent(s).
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Glycated haemoglobin A1c for diagnosing diabetes in Chinese population: cross sectional epidemiological survey
Yuqian Bao,Xiaojing Ma,Huating Li,Mi Zhou,Cheng Hu,Haiya Wu,Junling Tang,Xuhong Hou,Kun-san Xiang,Weiping Jia +9 more
TL;DR: An HbA1c threshold of 6.3% was highly specific for detecting undiagnosed diabetes in Chinese adults and had sensitivity similar to that of using a fasting plasma glucose threshold of 7.0 mmol/l, which may be suitable as a diagnostic criterion for diabetes when fasting Plasma glucose and oral glucose tolerance tests are not available.
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Upper limits of normal for alanine aminotransferase activity in the United States population
TL;DR: Alanine aminotransferase discriminates persons infected with HCV from those at low risk of liver disease, but would be considered elevated in a large proportion of the U.S. population.
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Rare and Common Genetic Events in Type 2 Diabetes: What Should Biologists Know?
TL;DR: The present review wishes to lift the fog around genetics of T2D with the hope that it will foster integrated diabetes modeling approaches from genetic defects to personalized medicine.
References
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Journal ArticleDOI
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin.
William C. Knowler,Elizabeth Barrett-Connor,Sarah E. Fowler,Richard F. Hamman,John M. Lachin,Elizabeth A. Walker,David M. Nathan +6 more
TL;DR: In this paper, the authors compared a lifestyle intervention with metformin to prevent or delay the development of Type 2 diabetes in nondiabetic individuals. And they found that the lifestyle intervention was significantly more effective than the medication.
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Hyperglycemia and adverse pregnancy outcomes
Boyd E. Metzger,Lynn P. Lowe,Alan R. Dyer,Elisabeth R. Trimble,Udom Chaovarindr,Donald R. Coustan,David R. Hadden,David R. McCance,Moshe Hod,Harold David McIntyre,Jeremy Oats,Bengt Persson,Michael S. Rogers,David A. Sacks +13 more
TL;DR: The results indicate strong, continuous associations of maternal glucose levels below those diagnostic of diabetes with increased birth weight and increased cord-blood serum C-peptide levels.
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International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy.
Pregnancy Study Groups Consensus Panel,Boyd E. Metzger,Steven G. Gabbe,Bengt Persson,Thomas A. Buchanan,Patrick A Catalano,Peter Damm,Alan R. Dyer,Alberto de Leiva,Moshe Hod,John L Kitzmiler,Lynn P. Lowe,H. David McIntyre,Jeremy Oats,Yasue Omori,Maria Inês Schmidt +15 more
TL;DR: The Brazilian study provided evidence that adverse perinatal outcomes are associated with levels of maternal glycemia below those diagnostic of GDM by American Diabetes Association or World Health Organization criteria, however, the results were potentially confounded by the treatment of G DM.
Journal ArticleDOI
Follow-up report on the diagnosis of diabetes mellitus.
Saul Genuth,K. G. M. M. Alberti,Peter H. Bennett,John B. Buse,Ralph A. DeFronzo,Richard Kahn,John L. Kitzmiller,William C. Knowler,Harold E. Lebovitz,Åke Lernmark,David M. Nathan,Jerry P. Palmer,Robbert Rizza,Christopher D Saudek,Jonathan E. Shaw,Michael W. Steffes,Michael P. Stern,Jaakko Tuomilehto,Paul Zimmet +18 more
TL;DR: The International Expert Committee was convened to reexamine the classification and diagnostic criteria of diabetes, which were based on the 1979 publication of the National Diabetes Data Group and subsequent WHO study group and adopted several changes to the diagnostic criteria for diabetes and for lesser degrees of impaired glucose regulation (IFG/IGT).
Journal ArticleDOI
Effect of treatment of gestational diabetes mellitus on pregnancy outcomes
Caroline A Crowther,Janet E. Hiller,John R. Moss,Andrew J McPhee,William S. Jeffries,Jeffrey S. Robinson +5 more
TL;DR: Treatment of gestational diabetes reduces serious perinatal morbidity and may also improve the woman's health-related quality of life.
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