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Journal ArticleDOI

Diagnosis and monitoring of hemorrhagic shock during the initial resuscitation of multiple trauma patients: a review

TLDR
Available technologies used to assess fluid status and tissue perfusion in patients with blood loss or hemorrhagic shock are reviewed, and how these methods can be used effectively and efficiently during initial trauma resuscitation to guide therapy and disposition are discussed.
Abstract
The initial management of the multiple trauma victim requires evaluation for potential hemorrhage and ongoing monitoring to assess the efficacy of resuscitation and avoid complications related to hemorrhagic shock. A variety of strategies exist to assess circulatory status, including hemodynamic monitoring, tissue perfusion measurement, and use of serum markers of metabolism. We review available technologies used to assess fluid status and tissue perfusion in patients with blood loss or hemorrhagic shock, discuss how these methods can be used effectively and efficiently during initial trauma resuscitation to guide therapy and disposition, and suggest directions for future research to improve outcomes by providing more appropriate and timely care and avoiding unnecessary complications.

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Journal ArticleDOI

Microvascular Blood Flow Is Altered in Patients with Sepsis

TL;DR: In conclusion, microvascular blood flow alterations are frequent in patients with sepsis and are more severe in Patients with a worse outcome.
Journal ArticleDOI

Characterization of the near infrared absorption spectra of cytochrome aa3 and haemoglobin for the non-invasive monitoring of cerebral oxygenation.

TL;DR: The cytochrome aa3 spectrum in vivo from the brains of rats after replacing the blood with a fluorocarbon substitute is obtained and an algorithm for calculating the changes in oxygenated and deoxygenated haemoglobin and oxygenated cy tochrome a a3 in tissue from changes in near IR absorption is constructed.
Journal ArticleDOI

Orthogonal polarization spectral imaging: a new method for study of the microcirculation.

TL;DR: Orthogonal polarization spectral (OPS) imaging is reported here on, a new method for imaging the microcirculation using reflected light that allows imaging of the micro Circulation noninvasively through mucus membranes and on the surface of solid organs.
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