Journal ArticleDOI
Diffusion of small molecular weight drugs in radiation-crosslinked poly(ethylene oxide) hydrogels
TLDR
In this article, a polyethylene oxide (PEO) hydrogel was formed by crosslinking of aqueous PEO solutions of M n = 35 000, 900 000 and 5 000 000 in concentrations of 5-50% using γ-irradiation with 3-10 Mrad.About:
This article is published in Journal of Controlled Release.The article was published on 1996-11-01. It has received 145 citations till now. The article focuses on the topics: Self-healing hydrogels & Diffusion.read more
Citations
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Hydrogels in Biology and Medicine: From Molecular Principles to Bionanotechnology†
TL;DR: This work highlights recent developments in engineering uncrosslinked and crosslinked hydrophilic polymers for biomedical and biological applications and shows how such systems' intelligent behavior can be used in sensors, microarrays, and imaging.
Journal ArticleDOI
Hydrogels in pharmaceutical formulations.
TL;DR: The aim of this article is to present a concise review on the applications of hydrogels in the pharmaceutical field, hydrogel characterization and analysis of drug release from such devices.
Journal ArticleDOI
Novel crosslinking methods to design hydrogels
Wim E. Hennink,C.F. van Nostrum +1 more
TL;DR: In this overview, different chemical and physical crosslinking methods used for the design of biodegradable hydrogels are summarized and discussed.
Journal ArticleDOI
Advances in Biomaterials, Drug Delivery, and Bionanotechnology
Robert Langer,Nicholas A. Peppas +1 more
TL;DR: Polymers as biomaterials, materials and approaches used in drug and protein delivery systems, materials used as scaffolds in tissue engineering, and nanotechnology and microfabrication techniques applied to biomaterialS are reviewed.
Journal ArticleDOI
Hydrogels in a historical perspective: from simple networks to smart materials.
Sytze J. Buwalda,Kristel W. M. Boere,Pieter J. Dijkstra,Jan Feijen,Tina Vermonden,Wim E. Hennink +5 more
TL;DR: A historical overview of the developments in hydrogel research from simple networks to smart materials is provided to overcome several challenges to overcome for clinical translation.
References
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Book
Hydrogels in Medicine and Pharmacy
TL;DR: Hydrogels in medicine and pharmacy, Hydrogel-like properties, and their applications in pharmacy and medicine are investigated.
BookDOI
Hydrogels in Medicine and Pharmacy : Fundamentals
TL;DR: In this paper, the authors discuss hydrogels in medicine and pharmacy and their applications in the field of medicine and pharmacology, including the use of hydrogel in medicine.
Journal ArticleDOI
Poly(vinyl alcohol) hydrogels: reinforcement of radiation-crosslinked networks by crystallization.
TL;DR: Aqueous poly(vinyl alcohol) solutions were crosslinked via electron-beam irradiation to form transparent hydrogels of varying crosslinking densities as discussed by the authors, which showed greatly improved mechanical properties (modulus, ultimate tensile strength, tear strength).
Journal ArticleDOI
Solute diffusion in swollen membranes. IX. Scaling laws for solute diffusion in gels
TL;DR: In this article, a scaling law for the diffusion coefficient of spheroidal and ellipsoidal solutes in nonporous, equilibrium-swollen hydrogels was developed.
Journal ArticleDOI
Partitioning and diffusion of solutes in hydrogels of poly(ethylene oxide)
TL;DR: Hydrogels were created by electron beam irradiation of aqueous solutions of poly(ethylene oxide) (PEO) having a nominal molecular weight of 35,000 and related to the hydrogel parameters Mc and v2,s and to the solute effective radius rE (Einstein radius).