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Journal ArticleDOI

Effect of Polysaccharides on the Properties of the Mucoadhesive Poly(Vinyl Alcohol) Multicore–Shell Microparticles

TLDR
In this article, the effect of polysaccharides (agar, gum tragacanth, and guar gum) on the properties of the core (organogel)-shell [poly(vinyl alcohol)] microparticles was discussed.
Abstract
This study discusses about the effect of polysaccharides (agar, gum tragacanth, and guar gum) on the properties of the core (organogel)–shell [poly(vinyl alcohol)] microparticles. The size, swelling, and mucoadhesive properties of the poly(vinyl alcohol) microparticles were altered in the presence of the polysaccharides. Thermal analysis confirmed the presence of organogels within the microparticles. Fourier transform infrared spectroscopy confirmed the presence of the polysaccharides within the microparticles. The microparticles were biocompatible in nature. Drug release indicated that an alteration in the shell composition can be used for altering drug release. Ciprofloxacin-loaded microparticles showed sufficient antimicrobial efficiency.

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Book ChapterDOI

Microscale Drug Delivery Systems: Current Perspectives and Novel Approaches

TL;DR: Drug delivery (DD), in general, represents a method of administering therapeutic complexes to biological systems that control and regulate various processes of liberation, absorption, dispersal, and elimination of biomedical entities.
References
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Journal ArticleDOI

Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC).

TL;DR: The present article is a comprehensive review of the current state of the art of mathematical modeling drug release from HPMC-based delivery systems and discusses the crucial points of the most important theories.
Journal ArticleDOI

Controlled Delivery Systems for Proteins Based on Poly(Lactic/Glycolic Acid) Microspheres

TL;DR: Stability studies showed that the encapsulation of an enzyme inside PLGA microspheres can protect them from activity loss, and in vitro release studies revealed that different release profiles and release rates can be achieved by simply modifying factors in the preparation procedure.
Journal ArticleDOI

Characterization of poly(vinyl alcohol)/poly(ethylene glycol) hydrogels and PVA-derived hybrids by small-angle X-ray scattering and FTIR spectroscopy

TL;DR: In this article, the authors developed novel polyvinyl alcohol (PVA)/poly(ethylene glycol) (PEG) hydrogel blends and PVA-derived organic-inorganic hybrid materials and performed nanostructural characterizations.
Journal ArticleDOI

Crosslinked ionic polysaccharides for stimuli-sensitive drug delivery.

TL;DR: The state of the art of crosslinked ionic polysaccharides as components of delivery systems that can regulate drug release as a function of changes in pH, ion nature and concentration, electric and magnetic field intensity, light wavelength, temperature, redox potential, and certain molecules are analyzed.
Journal ArticleDOI

Low viscosity hydrogel of guar gum: preparation and physicochemical characterization.

TL;DR: The low viscosity, the small amount of remained glutaraldehyde, and the thermal stability indicates that the guar hydrogel has potential to be applied as biomaterial with specific rheological requirements.
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