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Journal ArticleDOI

Estimation of dehydroascorbic acid in blood of diabetic patients

I. B. Chatterjee, +1 more
- 01 Oct 1979 - 
- Vol. 98, Iss: 2, pp 368-374
TLDR
The DHA from diabetic blood has been isolated as the 2,4-dinitrophenylhydrazone derivative and identified by thin-layer chromatography and spectrophotometry.
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This article is published in Analytical Biochemistry.The article was published on 1979-10-01. It has received 77 citations till now. The article focuses on the topics: Dehydroascorbic acid & Ascorbic acid.

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Citations
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Journal ArticleDOI

Characterization of dehydroascorbic acid solutions by liquid chromatography/mass spectrometry

TL;DR: Comparing data obtained for ascorbic acid (AA) solutions under the same experimental conditions revealed that, in the presence of light, the aging of such AA solutions gives rise to only the hemiketal form of DA, and that no dimeric species of DA were formed.
Journal ArticleDOI

Selected physical and biochemical parameters in the streptozotocin-treated guinea pig: insights into the diabetic guinea pig model.

TL;DR: A diabetic syndrome is demonstrated in the STZ-treated guinea pig based on a reduced growth rate, beta cell dysfunction, polydipsia, polyuria and glycosuria, and the usefulness of this diabetic model in studies of pathologic mechanisms influenced by ascorbic acid is suggested.
Journal ArticleDOI

Maternal Hyperglycemia and its Effect on the Placental Transport of Ascorbic acid

TL;DR: The data suggest that in the guinea pig glucose may compete with ascorbic acid transfer across the placenta and that maternal hyperglycemia may reduce the bioavailability of AA to the fetus.
Book ChapterDOI

Ascorbic acid and diabetes mellitus.

TL;DR: The cause of diabetic complications was initially an open question and subsequently became associated with hyperglycemia since elevated plasma glucose levels became increasingly viewed as the single outstanding feature which distinguished a diabetic from a nondiabetic individual.
Book ChapterDOI

Analysis of ascorbic acid, dehydroascorbic acid, and transformation products by ion-pairing high-performance liquid chromatography with multiwavelength ultraviolet and electrochemical detection.

TL;DR: In this paper, the analysis of ascorbic acid, dehydroascorbic acid and transformation products using ion-pairing high-performance liquid chromatography with multiwavelength ultraviolet and electrochemical detection is carried out by DEAE-Sepharose column chromatography.
References
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Book

Methods of Enzymatic Analysis

TL;DR: Methods of enzymatic analysis, Methods of enzymes analysis, the authors, Methods of enzyme analysis, enzymatics, methods of enzymes, and methods of analysis, method of enzymes.
Journal ArticleDOI

Synthesis and some major functions of vitamin C in animals.

TL;DR: Using the in vitro method, the ascorbic acid synthesizing abilities of different species of animals in the phylogenetic tree are examined, and the results are given below.
Journal ArticleDOI

The determination of diketo l-gulonic acid, dehydro-l-ascorbic acid, and l-ascorbic acid in the same tissue extract by the 2, 4-dinitrophenylhydrazine method.

TL;DR: Methods for determinations of vitamin C dehydro-Z-ascorbic (DHA), DHA, and DKA in the presence of each other are reported, indicating that these derivatives are identical substances.
Journal ArticleDOI

The use of homocysteine in the estimation of dehydroascorbic acid.

TL;DR: An account is given of a new method, based on the two findings that homocysteine rapidly reduces dehydroascorbic acid at pH 7 0, and that under certain simple conditions 2:6-dichlorophenolindophenol can be used to estimate ascorbic acid in the presence of homocy steine without interference from the latter compound.
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